中医对留置导尿管伴随性感染防治的文献分析(1)
摘 要：目的 分析中医在防治留置导尿管伴随性感染方面的研究状况，为今后的研究提供依据和方向。方法 以“中医OR中药”AND“感染”AND“尿管”为检索词，在中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据库、维普数据库(VIP)对采用中医方法防治CAUTI的文献进行检索和分析。结果 本次共检索出30篇文献，其中23篇为干预类研究，1篇综述，4篇经验或个案，涉及到的中医防治方法包括口服中药、膀胱内冲洗、中药外洗、针灸或综合治疗方法；2篇为基础研究，证实了中药的体外抑菌作用。结论 中医防治CAUTI的基础深厚，但研究刚刚起步，减少CAUTI的重点在于预防，保持尿道口清洁是重要环节；中药外洗法简单易行，无侵入性，患者接受度高，可进一步规范研究，为其在预防尤其是高危及特殊患者CAUTI提供循证依据。
关键词：留置导尿管伴随性感染；中医疗法；文献分析；数据库
中图分类号：R277.5 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.01.031
, http://www.100md.com
文章编号：1006-1959(2018)01-0088-04
Literature Analysis on the Prevention and Treatment of Adjoint Infection of Indwelling Catheter in Traditional Chinese Medicine
GE Ying-ying
(Jiangsu Provincial Hospital of Traditional Chinese Medicine/Department of Urology，Affiliated Hospital of Nanjing University of Traditional Chinese Medicine，Nanjing 200029，Jiangsu，China)
Abstract：Objective To analyze the research status of traditional Chinese medicine(TCM)in prevention and treatment of concomitant infection of indwelling catheter and provide basis and direction for future research.Methods The Chinese word"AND"and"AND"was used as a search term in Chinese traditional medicine"AND OR".The Chinese medicine method was used to prevent and treat the disease in Chinese biomedical literature database(CBM)，(CNKI)，Wanfang database and (VIP) database CAUTI's literature is searched and analyzed.Results A total of 30 articles were retrieved， of which 23 were interventional studies，1 review，4 experiences or cases.The methods of traditional Chinese medicine prevention and treatment involved oral Chinese medicine，intravesical irrigation，traditional Chinese medicine external washing，acupuncture or general treatment methods；2 for the basic research，confirmed the antibacterial effect of traditional Chinese medicine in vitro.Conclusion The foundation of traditional Chinese medicine(TCM) prevention and treatment of CAUTI is profound.However，the study has just started and the key to reduce CAUTI is to prevent and maintain the cleanliness of the urethra.It is simple，non-invasive and highly acceptable for patients.It can be further standardized，for its evidence of evidence-based prevention in CAUTI especially in high-risk and special patients.
, 百拇医药
Key words：Indwelling catheter associated with infection；Chinese medicine；Literature analysis；Database
留置導尿管伴随性相关感染，也称导尿管相关性感染(catheter associated urinary tract infection，CAUTI)，是最常见的院内感染，是指留置导尿管后，或者拔除导尿管后48 h所发生的泌尿系统感染[1]。在美国，CAUTI居院内死亡原因的第5位，留置导尿的患者中有30%会发生CAUTI，4%的患者可能出现菌血症或败血症，一旦发生，死亡率高达30%[2]，属于严重的公共卫生事件，威胁患者的生命安全的同时，也导致医疗保健成本的增加。2013年，美国卫生和人类服务部提出，计划将CAUTI降低50%[1]，并且早在2008年起美国医疗保险已经拒绝为院内导管性相关感染买单。在中国，泌尿系感染在院内感染中高居第二位，CAUTI的发生率约为53.8%[3]，留置超过14 d，发生率为97.6%[4]。因此CAUTI是医院关注的热点，众多的研究者从不同的角度研究降低CAUTI的方法。本文旨在回顾中医药防治CAUTI的研究，分析其现状和进展，为进一步研究提供方向。, 百拇医药(葛莹莹)
关键词：留置导尿管伴随性感染；中医疗法；文献分析；数据库
中图分类号：R277.5 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.01.031
, http://www.100md.com
文章编号：1006-1959(2018)01-0088-04
Literature Analysis on the Prevention and Treatment of Adjoint Infection of Indwelling Catheter in Traditional Chinese Medicine
GE Ying-ying
(Jiangsu Provincial Hospital of Traditional Chinese Medicine/Department of Urology，Affiliated Hospital of Nanjing University of Traditional Chinese Medicine，Nanjing 200029，Jiangsu，China)
Abstract：Objective To analyze the research status of traditional Chinese medicine(TCM)in prevention and treatment of concomitant infection of indwelling catheter and provide basis and direction for future research.Methods The Chinese word"AND"and"AND"was used as a search term in Chinese traditional medicine"AND OR".The Chinese medicine method was used to prevent and treat the disease in Chinese biomedical literature database(CBM)，(CNKI)，Wanfang database and (VIP) database CAUTI's literature is searched and analyzed.Results A total of 30 articles were retrieved， of which 23 were interventional studies，1 review，4 experiences or cases.The methods of traditional Chinese medicine prevention and treatment involved oral Chinese medicine，intravesical irrigation，traditional Chinese medicine external washing，acupuncture or general treatment methods；2 for the basic research，confirmed the antibacterial effect of traditional Chinese medicine in vitro.Conclusion The foundation of traditional Chinese medicine(TCM) prevention and treatment of CAUTI is profound.However，the study has just started and the key to reduce CAUTI is to prevent and maintain the cleanliness of the urethra.It is simple，non-invasive and highly acceptable for patients.It can be further standardized，for its evidence of evidence-based prevention in CAUTI especially in high-risk and special patients.
, 百拇医药
Key words：Indwelling catheter associated with infection；Chinese medicine；Literature analysis；Database
留置導尿管伴随性相关感染，也称导尿管相关性感染(catheter associated urinary tract infection，CAUTI)，是最常见的院内感染，是指留置导尿管后，或者拔除导尿管后48 h所发生的泌尿系统感染[1]。在美国，CAUTI居院内死亡原因的第5位，留置导尿的患者中有30%会发生CAUTI，4%的患者可能出现菌血症或败血症，一旦发生，死亡率高达30%[2]，属于严重的公共卫生事件，威胁患者的生命安全的同时，也导致医疗保健成本的增加。2013年，美国卫生和人类服务部提出，计划将CAUTI降低50%[1]，并且早在2008年起美国医疗保险已经拒绝为院内导管性相关感染买单。在中国，泌尿系感染在院内感染中高居第二位，CAUTI的发生率约为53.8%[3]，留置超过14 d，发生率为97.6%[4]。因此CAUTI是医院关注的热点，众多的研究者从不同的角度研究降低CAUTI的方法。本文旨在回顾中医药防治CAUTI的研究，分析其现状和进展，为进一步研究提供方向。, 百拇医药(葛莹莹)