生化检查与免疫检查在肾脏疾病临床诊治中的应用(1)
摘 要：目的 对比不同检查方法在肾脏疾病临床诊治中的应用价值。方法 选取2014年7月～2016年7月我院接收的肾脏疾病患者90例，按照检查方法的不同分为观察组和对照组，每组45例。观察组采用生化联合免疫学检查，对照组单纯采用免疫检查。另选取45例同期健康体检者为空白组。对比两组疾病诊断准确率、患者满意度以及实验室各指标。结果 观察组诊断准确率(95.56%)明显高于对照组(84.44%)，差异具有统计学意义(P<0.05)；观察组患者对检查方法的满意度评价(97.78%)远高于对照组(88.89%)，差异具有统计学意义(P<0.05)；与体检健康者相比，观察组与对照组白蛋白、补体C3、补体C4相比明显降低，而血清尿素、肌酐、尿酸明显升高，差异具有统计学意义(P<0.05)。结论 为肾脏疾病患者合理选择检查项目，采用生化免疫联合检查的方式可达到更高的诊断准确性，为临床诊疗提供重要参考依据，值得大力推广及应用。
关键词：生化检查；免疫检查；肾脏疾病
中图分类号：R692 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.02.055
, http://www.100md.com
文章编号：1006-1959(2018)02-0145-03
Abstract：Objective To compare the clinical value of different examination methods in the diagnosis and treatment of renal diseases.Methods 90 cases of renal diseases received from July 2014 to July 2016 in our hospital were selected.According to the different examination methods were divided into the observation group and the control group，each group of 45 cases，the observation group with biochemical combined immunological examination.The control group was only immunized.Another 45 healthy person were selected as the blank group.Compare the accuracy of diagnosis of two groups of diseases，patient satisfaction and laboratory indicators.Results The diagnostic accuracy of the observation group(95.56%)was significantly higher than that of the control group(84.44%)，the difference was statistically significant(P<0.05).The satisfaction rate of the observation group (97.78%) was much higher than that of the control group(88.89%)，the difference was statistically significant(P<0.05)；compared with healthy subjects，the observation group and control group albumin，complement C3，complement C4 was significantly lower，and serum urea，creatinine，uric acid was significantly increased，the difference was statistically significant(P<0.05).Conclusion It is a reasonable choice for the patients with kidney disease to check the project，and the biochemical and immunological joint examination can achieve higher diagnostic accuracy and provide an important reference for clinical diagnosis and treatment，which is worthy of promotion and application.
, 百拇医药
Key words：Biochemical tests；Immunological tests；Kidney diseases
腎脏不仅是人体排除代谢废物的主要器官，也是控制机体血压水平的重要系统[1]。由于肾脏疾病在发病早期缺乏特异性表现，使疾病不易被发现，一旦到确诊时通常已到了肾脏疾病的中晚期，对患者后期治疗十分不利。目前肾脏疾病利用生化检查和免疫检查方法效果满意[2]。为进一步突出何种检查方法在肾脏疾病的诊断中更具有实用价值，现选取我院2014年7月～2016年7月收治的90例肾脏疾病患者作为研究对象，报道如下。
1资料与方法
1.1一般资料 选取2014年7月～2016年7月本院接诊的90例肾脏疾病患者作为研究对象。纳入标准[3]：①所选患者均符合肾脏疾病的相关诊断标准，经病理检查确诊；②患者均无免疫性疾病，以及其他心血管疾病；③患者对于本次分组调查情况知情无异议，愿意积极配合。排除标准：①有其他心肺疾病；②未完成诊治计划；③临床资料不全；④不符合肾脏疾病诊断标准。所有患者按检查方法不同分为观察组与对照组各45例。对照组中男29例，女16例，年龄42～75岁，平均年龄(58.51±6.42)岁；肾脏疾病类型：肾小球疾病15例，肾炎11例，糖尿病型肾病8例，高血压型肾病7例，肾囊肿疾病4例。观察组中男38例，女17例，年龄43～76岁，平均年龄(58.79±6.25)岁；肾脏疾病类型：肾小球疾病14例，肾炎10例，糖尿病型肾病9例，高血压型肾病6例，肾囊肿疾病6例。另选取45例同期健康体检者为空白组，其中男28例，女17例，年龄21～65岁，平均年龄(43.12±5.24)岁。对比各组患者的临床资料，差异无统计学意义(P>0.05)，存在可比性。, http://www.100md.com(李志榕)
关键词：生化检查；免疫检查；肾脏疾病
中图分类号：R692 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.02.055
, http://www.100md.com
文章编号：1006-1959(2018)02-0145-03
Abstract：Objective To compare the clinical value of different examination methods in the diagnosis and treatment of renal diseases.Methods 90 cases of renal diseases received from July 2014 to July 2016 in our hospital were selected.According to the different examination methods were divided into the observation group and the control group，each group of 45 cases，the observation group with biochemical combined immunological examination.The control group was only immunized.Another 45 healthy person were selected as the blank group.Compare the accuracy of diagnosis of two groups of diseases，patient satisfaction and laboratory indicators.Results The diagnostic accuracy of the observation group(95.56%)was significantly higher than that of the control group(84.44%)，the difference was statistically significant(P<0.05).The satisfaction rate of the observation group (97.78%) was much higher than that of the control group(88.89%)，the difference was statistically significant(P<0.05)；compared with healthy subjects，the observation group and control group albumin，complement C3，complement C4 was significantly lower，and serum urea，creatinine，uric acid was significantly increased，the difference was statistically significant(P<0.05).Conclusion It is a reasonable choice for the patients with kidney disease to check the project，and the biochemical and immunological joint examination can achieve higher diagnostic accuracy and provide an important reference for clinical diagnosis and treatment，which is worthy of promotion and application.
, 百拇医药
Key words：Biochemical tests；Immunological tests；Kidney diseases
腎脏不仅是人体排除代谢废物的主要器官，也是控制机体血压水平的重要系统[1]。由于肾脏疾病在发病早期缺乏特异性表现，使疾病不易被发现，一旦到确诊时通常已到了肾脏疾病的中晚期，对患者后期治疗十分不利。目前肾脏疾病利用生化检查和免疫检查方法效果满意[2]。为进一步突出何种检查方法在肾脏疾病的诊断中更具有实用价值，现选取我院2014年7月～2016年7月收治的90例肾脏疾病患者作为研究对象，报道如下。
1资料与方法
1.1一般资料 选取2014年7月～2016年7月本院接诊的90例肾脏疾病患者作为研究对象。纳入标准[3]：①所选患者均符合肾脏疾病的相关诊断标准，经病理检查确诊；②患者均无免疫性疾病，以及其他心血管疾病；③患者对于本次分组调查情况知情无异议，愿意积极配合。排除标准：①有其他心肺疾病；②未完成诊治计划；③临床资料不全；④不符合肾脏疾病诊断标准。所有患者按检查方法不同分为观察组与对照组各45例。对照组中男29例，女16例，年龄42～75岁，平均年龄(58.51±6.42)岁；肾脏疾病类型：肾小球疾病15例，肾炎11例，糖尿病型肾病8例，高血压型肾病7例，肾囊肿疾病4例。观察组中男38例，女17例，年龄43～76岁，平均年龄(58.79±6.25)岁；肾脏疾病类型：肾小球疾病14例，肾炎10例，糖尿病型肾病9例，高血压型肾病6例，肾囊肿疾病6例。另选取45例同期健康体检者为空白组，其中男28例，女17例，年龄21～65岁，平均年龄(43.12±5.24)岁。对比各组患者的临床资料，差异无统计学意义(P>0.05)，存在可比性。, http://www.100md.com(李志榕)