髓芯减压联合同种异体骨打压植骨治疗早期股骨头坏死的疗效观察(1)
摘 要：目的 探讨髓芯减压联合同种异体骨打压植骨治疗早期股骨头坏死的临床疗效。方法 采用随机数字表法将2016年1月～2017年6月于我院诊治的早期股骨头坏死患者40例分为两组，各20例。对照组采用多孔钽棒植入治疗，观察组行髓芯减压联合同种异体骨打压植骨治疗，比较两组患者治疗前后Harris髋关节评分及临床疗效。结果 治疗前两组患者Harris评分差异无统计学意义(P>0.05)，治疗后观察组Harris评分优于对照组[(82.56±8.42)分 vs (74.53±7.31)分]，差异有统计学意义(P<0.05)；观察组治疗总有效率高于对照组，组间差异有统计学意义(P<0.05)。结论 早期股骨头坏死患者选择髓芯减压+同种异体骨打压植骨治疗效果显著，可充分改善患者髋关节功能，促使患者尽早康复，值得临床上广泛应用。
关键词：早期股骨头坏死；髓芯减压；同种异体骨打压植骨
中图分类号：R687.3 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.04.030
, 百拇医药
文章编号：1006-1959(2018)04-0093-03
Abstract：Objective To investigate the clinical effect of decompression combined with allogenic bone grafting in the treatment of early femoral head necrosis.Methods 40 patients with early stage of osteonecrosis of the femoral head who were diagnosed and treated in our hospital from January 2016 to June 2017 were divided into two groups (n=20) by random number table.The control group was treated with porous tantalum rod implantation.The observation group was treated with core decompression combined with allograft bone grafting.The Harris hip score and clinical treatment effect were compared between the two groups before and after treatment.Results There was no significant difference in Harris score between the two groups before treatment (P>0.05).After treatment，the Harris score in the observation group was superior to that in the control group[(82.56±8.42)vs(74.53±7.31)]，the difference was statistically significant (P<0.05).The total effective rate of the observation group was higher than that of the control group，the difference was statistically significant(P<0.05). Conclusion The treatment of early femoral head necrosis by core decompression combined with allogenic bone impaction bone grafting has significant effect，which can fully improve the hip joint function and promote the recovery of patients as soon as possible，which deserves to be widely used clinically.
, 百拇医药
Key words：Early osteonecrosis of femoral head；Core decompression；Allograft bone impaction bone graft
股骨頭坏死(osteonecrosis of femoral head，ONFH)为骨科常见疾病之一，临床上多见患者股骨头血供损伤/中断，使得股骨头结构及关节间隙发生改变，患者均伴有髋关节疼痛、功能障碍[1]。临床治疗早期股骨头坏死的手术方式较多，但其各有不同的适应证与优缺点，此次研究为两组患者应用不同的方式治疗，对髓芯减压+同种异体骨打压植骨治疗早期股骨头坏死的疗效进行探讨，现报道如下。
1 资料与方法
1.1一般资料 以随机数字表法将2016年1月～2017年6月于我院诊治的40例早期股骨头坏死患者分为对照组与观察组，各20例。对照组中男8例，女12例，年龄23～52岁，平均年龄(39.15±8.32)岁；观察组中男6例，女14例，年龄25～50岁，平均年龄(39.62±8.37)岁。两组患者性别、年龄比较差异无统计学意义(P>0.05)。
1.2入选和排除标准 ①纳入标准[1]：患者均符合《成人股骨头坏死诊疗标准专家共识》中相关诊断标准；于本院住院治疗的Ⅰ期、Ⅱa期股骨头坏死的患者；纳入年龄20～55岁的患者；机体不存在外伤史的患者；经本院伦理委员批准并允许参加研究的患者；对本次研究中各项内容均知晓并签署知情同意书的患者。②排除标准：具体情况与上述诊断标准相关内容不符合的患者；合并全身/局部感染的患者；合并心、肝、肾等重大器官疾病的患者；合并糖尿病、高血压、消化系统等基础疾病的患者；精神障碍、语言障碍而不能配合研究内容的患者；临床资料不全者。, http://www.100md.com(何骏)
关键词：早期股骨头坏死；髓芯减压；同种异体骨打压植骨
中图分类号：R687.3 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.04.030
, 百拇医药
文章编号：1006-1959(2018)04-0093-03
Abstract：Objective To investigate the clinical effect of decompression combined with allogenic bone grafting in the treatment of early femoral head necrosis.Methods 40 patients with early stage of osteonecrosis of the femoral head who were diagnosed and treated in our hospital from January 2016 to June 2017 were divided into two groups (n=20) by random number table.The control group was treated with porous tantalum rod implantation.The observation group was treated with core decompression combined with allograft bone grafting.The Harris hip score and clinical treatment effect were compared between the two groups before and after treatment.Results There was no significant difference in Harris score between the two groups before treatment (P>0.05).After treatment，the Harris score in the observation group was superior to that in the control group[(82.56±8.42)vs(74.53±7.31)]，the difference was statistically significant (P<0.05).The total effective rate of the observation group was higher than that of the control group，the difference was statistically significant(P<0.05). Conclusion The treatment of early femoral head necrosis by core decompression combined with allogenic bone impaction bone grafting has significant effect，which can fully improve the hip joint function and promote the recovery of patients as soon as possible，which deserves to be widely used clinically.
, 百拇医药
Key words：Early osteonecrosis of femoral head；Core decompression；Allograft bone impaction bone graft
股骨頭坏死(osteonecrosis of femoral head，ONFH)为骨科常见疾病之一，临床上多见患者股骨头血供损伤/中断，使得股骨头结构及关节间隙发生改变，患者均伴有髋关节疼痛、功能障碍[1]。临床治疗早期股骨头坏死的手术方式较多，但其各有不同的适应证与优缺点，此次研究为两组患者应用不同的方式治疗，对髓芯减压+同种异体骨打压植骨治疗早期股骨头坏死的疗效进行探讨，现报道如下。
1 资料与方法
1.1一般资料 以随机数字表法将2016年1月～2017年6月于我院诊治的40例早期股骨头坏死患者分为对照组与观察组，各20例。对照组中男8例，女12例，年龄23～52岁，平均年龄(39.15±8.32)岁；观察组中男6例，女14例，年龄25～50岁，平均年龄(39.62±8.37)岁。两组患者性别、年龄比较差异无统计学意义(P>0.05)。
1.2入选和排除标准 ①纳入标准[1]：患者均符合《成人股骨头坏死诊疗标准专家共识》中相关诊断标准；于本院住院治疗的Ⅰ期、Ⅱa期股骨头坏死的患者；纳入年龄20～55岁的患者；机体不存在外伤史的患者；经本院伦理委员批准并允许参加研究的患者；对本次研究中各项内容均知晓并签署知情同意书的患者。②排除标准：具体情况与上述诊断标准相关内容不符合的患者；合并全身/局部感染的患者；合并心、肝、肾等重大器官疾病的患者；合并糖尿病、高血压、消化系统等基础疾病的患者；精神障碍、语言障碍而不能配合研究内容的患者；临床资料不全者。, http://www.100md.com(何骏)