悬浮红细胞联合手工分冰冻血浆输注对大量输血患者凝血四项指标变化的影响(1)
摘 要：目的 探究懸浮红细胞联合手工分冰冻血浆输注对大量输血患者凝血四项指标变化的影响。方法 选取2013年9月～2017年4月我院58例大量输血患者，依据输血方式不同分组，各29例。对照组输入悬浮红细胞，于此基础上，实验组输入手工分冰冻血浆。对比两组大量输血前及输血后第1、3、5 天凝血四项指标水平。结果 输血前，两组凝血四项指标FIB、TT、APTT、PT水平相比，差异无统计学意义(P>0.05)；输血后第1天，两组FIB水平较输血前下降，TT、APTT、PT水平较输血前上升，差异有统计学意义(P<0.05)；输血后第3 、5天，两组FIB水平较输血后第1天上升，TT、APTT、PT水平较输血后1 d下降，差异有统计学意义(P<0.05)；输血后第5天，实验组凝血四项指标FIB、TT、APTT、PT水平均基本恢复至输血前水平，差异有统计学意义(P>0.05)；且输血后第1、3、5天 ，实验组FIB水平较对照组高，TT、APTT、PT水平均较对照组低，差异有统计学意义(P<0.05)。结论 对大量输血患者联合输注悬浮红细胞、手工分冰冻血浆，有助于改善凝血功能，提高输血疗效，在临床治疗中具有重要意义。
, http://www.100md.com
关键词：悬浮红细胞；手工分冰冻血浆；大量输血；凝血四项
中图分类号：R446.11 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.08.051
文章编号：1006-1959(2018)08-0146-03
Effect of Suspended Red Blood Cells Combined with Manual Frozen Plasma Infusion on the Changes of Four Indexes of Blood Coagulation in Massive Transfusion Patients
LI Zhong-fa
(Department of Blood Source，Jiamusi Central Blood Station，Jiamusi 154007，Heilongjinng，China)
, 百拇医药
Abstract：Objective To explore the effect of suspended red blood cells combined with manual frozen plasma transfusion on the four coagulation parameters in patients with massive blood transfusion.Methods From September 2013 to April 2017，58 patients with massive blood transfusion in our hospital were divided into different groups，29 cases each.The control group received suspended red blood cells，on this basis，the experimental group imported frozen plasma manually.The blood coagulation indexes of two groups before and first，third，fifth days after transfusion were compared between the four groups.Results Before blood transfusion，there was no significant difference between the two groups of blood coagulation four indexes FIB，TT，APTT and PT(P>0.05)；first days after blood transfusion，two groups of FIB levels were lower than those before blood transfusion，TT，APTT and PT were higher than those before blood transfusion，and the difference was statistically significant (P<0.05)；Third，fifth days after blood transfusion，the level of FIB in two groups was higher than that of first days after blood transfusion，and the levels of TT，APTT and PT were lower than 1 d after blood transfusion，the difference was statistically significant(P<0.05).The level of four indexes of FIB，TT，APTT and PT in the experimental group all recovered to the level before blood transfusion at fifth days after blood transfusion，and the difference was statistically significant(P>0.05).And first，third，fifth days after blood transfusion，the level of FIB in the experimental group was higher than that of the control group，and the levels of TT，APTT and PT were lower than those of the control group，and the difference was statistically significant(P<0.05).Conclusion The combination of transfusion of red blood cells and frozen plasma in a large number of blood transfusion patients will help to improve the function of blood coagulation and improve the curative effect of blood transfusion，which is of great significance in clinical treatment., 百拇医药(李忠法)
, http://www.100md.com
关键词：悬浮红细胞；手工分冰冻血浆；大量输血；凝血四项
中图分类号：R446.11 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.08.051
文章编号：1006-1959(2018)08-0146-03
Effect of Suspended Red Blood Cells Combined with Manual Frozen Plasma Infusion on the Changes of Four Indexes of Blood Coagulation in Massive Transfusion Patients
LI Zhong-fa
(Department of Blood Source，Jiamusi Central Blood Station，Jiamusi 154007，Heilongjinng，China)
, 百拇医药
Abstract：Objective To explore the effect of suspended red blood cells combined with manual frozen plasma transfusion on the four coagulation parameters in patients with massive blood transfusion.Methods From September 2013 to April 2017，58 patients with massive blood transfusion in our hospital were divided into different groups，29 cases each.The control group received suspended red blood cells，on this basis，the experimental group imported frozen plasma manually.The blood coagulation indexes of two groups before and first，third，fifth days after transfusion were compared between the four groups.Results Before blood transfusion，there was no significant difference between the two groups of blood coagulation four indexes FIB，TT，APTT and PT(P>0.05)；first days after blood transfusion，two groups of FIB levels were lower than those before blood transfusion，TT，APTT and PT were higher than those before blood transfusion，and the difference was statistically significant (P<0.05)；Third，fifth days after blood transfusion，the level of FIB in two groups was higher than that of first days after blood transfusion，and the levels of TT，APTT and PT were lower than 1 d after blood transfusion，the difference was statistically significant(P<0.05).The level of four indexes of FIB，TT，APTT and PT in the experimental group all recovered to the level before blood transfusion at fifth days after blood transfusion，and the difference was statistically significant(P>0.05).And first，third，fifth days after blood transfusion，the level of FIB in the experimental group was higher than that of the control group，and the levels of TT，APTT and PT were lower than those of the control group，and the difference was statistically significant(P<0.05).Conclusion The combination of transfusion of red blood cells and frozen plasma in a large number of blood transfusion patients will help to improve the function of blood coagulation and improve the curative effect of blood transfusion，which is of great significance in clinical treatment., 百拇医药(李忠法)