老年脑卒中后抑郁及血管性认知功能障碍的研究分析(1)
摘 要：目的 探讨老年卒中患者的抑郁障碍及血管性认知功能障碍发生情况，并进一步研究卒中患者抑郁障碍与血管性认知功能障碍的关系。方法 随机选取我院2016年1月～2017年8月治疗的204例老年卒中患者，采用汉密尔顿抑郁量表、蒙特利尔认知评估量表和简明精神状态检查量表对卒中患者进行评估，观察患者抑郁障碍发生率、血管性认知功能障碍、HAMD得分、MoCA得分及MMSE得分情况。结果 老年卒中患者的抑郁障碍发生率为52.45%，不同年龄间的抑郁障碍发生率，差异有统计学意义(P<0.05)；抑郁障碍患者的血管性认知功能障碍的发生率，高于非抑郁障碍患者(P<0.05)；不同程度的抑郁障碍患者发生血管性认知功能障碍，差异有统计学意义(P<0.05)；卒中患者的HAMD得分与MoCA得分及MMSE得分呈负相关(P<0.05)。结论 老年卒中患者的抑郁障碍及血管性认知功能障碍发病率较高，抑郁障碍的发生对血管性认知功能障碍的发生具有一定影响。
关键词：老年；卒中后抑郁；血管性认知功能障碍；发病率；相关性
, http://www.100md.com
中图分类号：R473.74 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.09.029
文章编号：1006-1959(2018)09-0098-03
Abstract：Objective To investigate the incidence of depressive disorder and vascular cognitive impairment in elderly patients with stroke， and to further study the relationship between depressive disorder and vascular cognitive impairment in stroke patients.Methods A total of 204 elderly patients with stroke who were treated in our hospital from January 2016 to August 2017 were randomly selected and assessed by the Hamilton Depression Scale，Montreal Cognitive Assessment Scale，and Concise Mental State Examination Scale.The patients were observed for depression.Incidence of disorders，vascular cognitive impairment，HAMD score， MoCA score，and MMSE score.Results The incidence of depressive disorder in elderly patients with stroke was 52.45%，and the incidence of depressive disorder in different ages was statistically significant(P<0.05)；the incidence of vascular cognitive impairment in depressive patients was higher than that of non depressive disorder patients(P<0.05)；vascular cognitive work in patients with different degrees of depressive disorder occurred，the difference was statistically significant(P<0.05)；the HAMD score of stroke patients was negatively correlated with MoCA score and MMSE score(P<0.05).Conclusion The incidence of depressive disorder and vascular cognitive impairment in elderly patients with stroke is higher，and the occurrence of depressive disorder has a certain influence on the occurrence of vascular cognitive impairment.
, 百拇医药
Key words：Elderly；Post-stroke depression；Vascular cognitive impairment；Incidence；Correlation
卒中后抑郁障礙(post-stroke depression，PSD)是脑卒中的常见并发症之一，是指在有明显临床症状的脑卒中发作后出现的抑郁，属于继发性抑郁[1]。血管性认知功能障碍(vascular cognitive impairment，VCI)也是脑卒中患者的常见症状之一 [2]。研究数据显示我国脑卒中的患病率较高，每年新发脑卒中患者超过200万[3]，脑卒中患者有着较高的死亡率，并严重影响患者的健康。临床观察发现，卒中后抑郁障碍与血管性认知障碍相伴发生[4]，本文通过对患者的抑郁及认知功能的评价，探讨脑卒中患者抑郁状态与血管认知功能障碍之间的关系，以改善患者的预后及提供其生活质量，现分析如下。
1资料与方法
1.1一般资料 选取浙江省公安边防总队医院2016年1月～2017年8月就诊204例卒中患者作为研究对象，该研究通过我院医学伦理委员会审核。其中男性103例，女性101例，年龄60～84岁，平均年龄(72.35±9.51)岁，病程0～3个月，平均病程(1.39±0.78)个月。纳入标准：①年龄≥60岁；②取得患者知情同意；③所有患者均经过头颅CT或MR扫描，并且诊断符合全国脑血管病会议指定的标准[5]；④卒中发生3个月内且病情稳定者；⑤无意识障碍且无严重听力、视力和语言障碍，具有一定的阅读和听写能力；⑥所有患者均为首次发生缺血性脑卒中，并且排除其他脑部疾病。排除标准：①卒中后病情严重或伴有意识障碍不能配合检查者；②患有严重心、肝、肺、肾、血液等系统疾病者。, http://www.100md.com(熊继红 江亚琴 徐国丽)
关键词：老年；卒中后抑郁；血管性认知功能障碍；发病率；相关性
, http://www.100md.com
中图分类号：R473.74 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.09.029
文章编号：1006-1959(2018)09-0098-03
Abstract：Objective To investigate the incidence of depressive disorder and vascular cognitive impairment in elderly patients with stroke， and to further study the relationship between depressive disorder and vascular cognitive impairment in stroke patients.Methods A total of 204 elderly patients with stroke who were treated in our hospital from January 2016 to August 2017 were randomly selected and assessed by the Hamilton Depression Scale，Montreal Cognitive Assessment Scale，and Concise Mental State Examination Scale.The patients were observed for depression.Incidence of disorders，vascular cognitive impairment，HAMD score， MoCA score，and MMSE score.Results The incidence of depressive disorder in elderly patients with stroke was 52.45%，and the incidence of depressive disorder in different ages was statistically significant(P<0.05)；the incidence of vascular cognitive impairment in depressive patients was higher than that of non depressive disorder patients(P<0.05)；vascular cognitive work in patients with different degrees of depressive disorder occurred，the difference was statistically significant(P<0.05)；the HAMD score of stroke patients was negatively correlated with MoCA score and MMSE score(P<0.05).Conclusion The incidence of depressive disorder and vascular cognitive impairment in elderly patients with stroke is higher，and the occurrence of depressive disorder has a certain influence on the occurrence of vascular cognitive impairment.
, 百拇医药
Key words：Elderly；Post-stroke depression；Vascular cognitive impairment；Incidence；Correlation
卒中后抑郁障礙(post-stroke depression，PSD)是脑卒中的常见并发症之一，是指在有明显临床症状的脑卒中发作后出现的抑郁，属于继发性抑郁[1]。血管性认知功能障碍(vascular cognitive impairment，VCI)也是脑卒中患者的常见症状之一 [2]。研究数据显示我国脑卒中的患病率较高，每年新发脑卒中患者超过200万[3]，脑卒中患者有着较高的死亡率，并严重影响患者的健康。临床观察发现，卒中后抑郁障碍与血管性认知障碍相伴发生[4]，本文通过对患者的抑郁及认知功能的评价，探讨脑卒中患者抑郁状态与血管认知功能障碍之间的关系，以改善患者的预后及提供其生活质量，现分析如下。
1资料与方法
1.1一般资料 选取浙江省公安边防总队医院2016年1月～2017年8月就诊204例卒中患者作为研究对象，该研究通过我院医学伦理委员会审核。其中男性103例，女性101例，年龄60～84岁，平均年龄(72.35±9.51)岁，病程0～3个月，平均病程(1.39±0.78)个月。纳入标准：①年龄≥60岁；②取得患者知情同意；③所有患者均经过头颅CT或MR扫描，并且诊断符合全国脑血管病会议指定的标准[5]；④卒中发生3个月内且病情稳定者；⑤无意识障碍且无严重听力、视力和语言障碍，具有一定的阅读和听写能力；⑥所有患者均为首次发生缺血性脑卒中，并且排除其他脑部疾病。排除标准：①卒中后病情严重或伴有意识障碍不能配合检查者；②患有严重心、肝、肺、肾、血液等系统疾病者。, http://www.100md.com(熊继红 江亚琴 徐国丽)