螺旋CT结合钼靶X线在乳腺癌早期诊断中的应用(1)
摘要：目的 分析螺旋CT结合钼靶X线在乳腺癌早期诊断中的应用价值。方法 选取2017年4月～2018年4月至我院就诊的乳腺癌患者80例，均接受螺旋CT检查与钼靶X线检查，以病理检查为标准，比较两种检查方法单独检查及联合检查的准确率。结果 钼靶X线检测阳性率及CT检查阳性率均较病理检查阳性率低，差异有统计学意义(P<0.05);钼靶X线联合CT检查阳性率与病理检查阳性比较，差异无统计学意义(P>0.05);单独采用螺旋CT、钼靶X线与二者联合诊断检测乳腺癌的特异度比较，差异无统计学意义(P>0.05);钼靶X线的检测准确率低于联合诊断 (P<0.05)，而螺旋CT与联合诊断的检测准确率比较，差异无统计学意义(P>0.05);联合诊断的灵敏度为96.00%，高于单独使用钼靶X线的84.00%及螺旋CT 的85.33%，差异有统计学意义(P<0.05)。结论 螺旋CT与钼靶X线二者联合应用相较于二者单项诊断，其在准确率、灵敏度上具有一定优势，可以作为临床乳腺癌早期诊断的可靠手段。
关键词：乳腺癌;螺旋CT;钼靶X线
, http://www.100md.com
中图分类号：R730.44;R737.9 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.03.059
文章编号：1006-1959(2019)03-0173-02
Abstract：Objective To analyze the value of spiral CT combined with molybdenum target X-ray in early diagnosis of breast cancer. Methods 80 patients with breast cancer in our hospital from April 2017 to April 2018 were selected.All of them were examined by spiral CT andmolybdenum target X-ray.Pathological examination was regarded as the standard.The accuracy of the separate and combined methods was compared.Results The positive rate ofmolybdenum target X-ray and CT was lower than that of pathological examination，the difference was statistically significant (P<0.05).The positive rate ofmolybdenum target X-ray combined with CT was not significantly different from that of pathological examination (P>0.05).There was no significant difference in the specificity of the detection of breast cancer by spiral CT，molybdenum target X-ray and combined diagnosis (P>0.05).The accuracy of X-ray detection of molybdenum target was lower than that of combined diagnosis (P<0.05)，but there was no significant difference between spiral CT and combined diagnosis (P>0.05).The sensitivity of combined diagnosis was 96.00%， which was significantly higher than that of molybdenum target X-ray alone 84.00% and spiral CT 85.33%，the difference was statistically significant(P<0.05).Conclusion The combination of spiral CT and molybdenum target X-ray has some advantages in accuracy and sensitivity， and can be used as a reliable method for early diagnosis of clinical breast cancer.
, 百拇医药
Key words：Breast cancer;Spiral CT;Molybdenum target X-ray
乳腺癌(mammary cancer)是發生在乳腺腺上皮组织的恶性肿瘤，女性占99%，男性仅占1%[1]。原位乳腺癌并不致命，但由于乳腺癌细胞丧失了正常细胞的特性，细胞间连接蛋白减少，易导致细胞从原位置脱离，游离的癌细胞可以随血液或淋巴液播散全身，形成多器官转移和浸润，进而危及患者生命[2]。近年我国乳腺癌发病率的增速已高出以往乳腺癌高发国家1～2个百分点。目前，全国乳腺癌发病率居女性恶性肿瘤第1位，成为威胁女性身心健康的最常见恶性疾病[3]。现今临床上针对乳腺癌的早期诊断方法主要包括螺旋CT及钼靶X线，均具有较高的阳性检出率，为提高乳腺癌患者早期诊断准确率，本研究拟对我院乳腺科诊治的80例乳腺癌患者采用螺旋CT检查与钼靶X线检查，对比以上两种方式单独检查及联合检查准确率，并分别与病理检查结果进行比较，旨在为临床更精准、更有效的乳腺癌早期诊断提供理论依据，现报道如下。, 百拇医药(李百鑫)
关键词：乳腺癌;螺旋CT;钼靶X线
, http://www.100md.com
中图分类号：R730.44;R737.9 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.03.059
文章编号：1006-1959(2019)03-0173-02
Abstract：Objective To analyze the value of spiral CT combined with molybdenum target X-ray in early diagnosis of breast cancer. Methods 80 patients with breast cancer in our hospital from April 2017 to April 2018 were selected.All of them were examined by spiral CT andmolybdenum target X-ray.Pathological examination was regarded as the standard.The accuracy of the separate and combined methods was compared.Results The positive rate ofmolybdenum target X-ray and CT was lower than that of pathological examination，the difference was statistically significant (P<0.05).The positive rate ofmolybdenum target X-ray combined with CT was not significantly different from that of pathological examination (P>0.05).There was no significant difference in the specificity of the detection of breast cancer by spiral CT，molybdenum target X-ray and combined diagnosis (P>0.05).The accuracy of X-ray detection of molybdenum target was lower than that of combined diagnosis (P<0.05)，but there was no significant difference between spiral CT and combined diagnosis (P>0.05).The sensitivity of combined diagnosis was 96.00%， which was significantly higher than that of molybdenum target X-ray alone 84.00% and spiral CT 85.33%，the difference was statistically significant(P<0.05).Conclusion The combination of spiral CT and molybdenum target X-ray has some advantages in accuracy and sensitivity， and can be used as a reliable method for early diagnosis of clinical breast cancer.
, 百拇医药
Key words：Breast cancer;Spiral CT;Molybdenum target X-ray
乳腺癌(mammary cancer)是發生在乳腺腺上皮组织的恶性肿瘤，女性占99%，男性仅占1%[1]。原位乳腺癌并不致命，但由于乳腺癌细胞丧失了正常细胞的特性，细胞间连接蛋白减少，易导致细胞从原位置脱离，游离的癌细胞可以随血液或淋巴液播散全身，形成多器官转移和浸润，进而危及患者生命[2]。近年我国乳腺癌发病率的增速已高出以往乳腺癌高发国家1～2个百分点。目前，全国乳腺癌发病率居女性恶性肿瘤第1位，成为威胁女性身心健康的最常见恶性疾病[3]。现今临床上针对乳腺癌的早期诊断方法主要包括螺旋CT及钼靶X线，均具有较高的阳性检出率，为提高乳腺癌患者早期诊断准确率，本研究拟对我院乳腺科诊治的80例乳腺癌患者采用螺旋CT检查与钼靶X线检查，对比以上两种方式单独检查及联合检查准确率，并分别与病理检查结果进行比较，旨在为临床更精准、更有效的乳腺癌早期诊断提供理论依据，现报道如下。, 百拇医药(李百鑫)