血常规在缺铁性贫血和珠蛋白生成障碍性贫血鉴别诊断中的应用(1)
摘要：目的 探究血常规鉴别诊断缺铁性贫血和珠蛋白生成障碍性贫血的方法及临床应用价值。方法 选取2017年1月～2018年1月在本院确诊并行治疗的贫血患者为研究对象，按照疾病分型将缺铁性贫血38例设为甲组，珠蛋白生成障碍贫血42例设为乙组，选取同期接受体检的健康者40例设对照组，比较3组血常规各项指标。结果 甲组、乙组HGB、MCV、MCH、MCHC水平均低于对照组，甲组、乙组的RDW水平高于对照组，乙组的RBC(4.78±0.79)1012/L、RDW(0.20±0.02)%、HGB(94.29±6.58)g/L、均高于甲組，乙组RBC(4.78±0.79)1012/L高于对照组，甲组RBC(3.55±0.63)1012/L低于对照组，差异均有统计学意义(P<0.05)。结论 血常规检测结果可以作为鉴别诊断缺铁性贫血和珠蛋白生成障碍性贫血的方法。
关键词：珠蛋白生成障碍;缺铁性贫血;血常规检验;鉴别方法
中图分类号：R446.11+1;R556 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.08.054
, 百拇医药
文章编号：1006-1959(2019)08-0171-03
Abstract：Objective To explore the method and clinical value of blood routine differential diagnosis of iron deficiency anemia and globin-producing anemia. Methods The patients with anemia diagnosed in our hospital from January 2017 to January 2018 were enrolled in the study. According to the disease classification， 38 cases of iron deficiency anemia were set as group A， and 42 cases of globin-forming anemia were set as B. In the group， 40 healthy subjects who underwent physical examination at the same time were selected as the control group， and the blood routine indicators of the 3 groups were compared. Results The levels of HGB， MCV， MCH and MCHC in group A and group B were lower than those in the control group. The RDW level of group A and group B was higher than that of the control group. The RBC of group B was (4.78±0.79) 1012/L， RDW (0.20±0.02)%， HGB (94.29±6.58) g/L were higher than group A， group B RBC (4.78±0.79) 1012/L was higher than the control group， group A RBC (3.55±0.63) 1012/L was lower than the control group，the differences were statistically significant (P<0.05). Conclusion Blood routine test results can be used as a method to differentially diagnose iron deficiency anemia and globin-producing anemia.
, 百拇医药
Key words：Globin production barrier;Iron deficiency anemia;Blood routine test;Identification method
贫血(anemia)是临床中常见的血液疾病，常表现为脸色苍白、乏力、食欲不振、易疲倦等，原因为造血物质缺乏、造血功能障碍、红细胞破坏过多和大量出血等，以缺铁性贫血和珠蛋白生成障碍在临床中最为常见[1]。虽然缺铁性贫血和珠蛋白生成障碍性贫血同属于小细胞低色素性贫血，然而两者在病因、发病机制、治疗上截然不同。因此在临床需要对上述两种贫血类型进行准确诊断鉴别，从而为临床治疗提供可靠依据十分重要[2]。血常规检验是临床常用的检验方法，其操作简便，标本易得，结果直观，是很多疾病诊断常用的方法。本研究运用血常规检测方法及结果来鉴别诊断缺铁性贫血和珠蛋白生成障碍性贫血，对血常规鉴别诊断两者的临床效果进行分析。
1资料与方法
1.1一般资料 选择佳木斯市中医院2017年1月～2018年1月确诊收治的贫血患者80例。本研究已经过医院医学伦理委员会同意，所有研究对象均知情同意并签署知情同意书。按照贫血类型分为甲、乙组，其中甲组为缺铁性贫血患者38例，男16例，女22例;年龄19～63岁，平均年龄(38.91±5.12)岁;病程4个月～5年，平均病程(2.25±0.53)年; 乙组42例均为珠蛋白生成障碍性贫血患者，其中男19例，女23例，年龄19～57岁，平均年龄(38.76±4.21)岁; 病程3个月～6年，平均病程(2.04±0.76)年;另选择同期在本院中接受体检的健康者40例设为对照组，其中男24例，女16例;年龄20～65 岁，平均年龄(39.25±5.06)岁。, http://www.100md.com(吴云)
关键词：珠蛋白生成障碍;缺铁性贫血;血常规检验;鉴别方法
中图分类号：R446.11+1;R556 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.08.054
, 百拇医药
文章编号：1006-1959(2019)08-0171-03
Abstract：Objective To explore the method and clinical value of blood routine differential diagnosis of iron deficiency anemia and globin-producing anemia. Methods The patients with anemia diagnosed in our hospital from January 2017 to January 2018 were enrolled in the study. According to the disease classification， 38 cases of iron deficiency anemia were set as group A， and 42 cases of globin-forming anemia were set as B. In the group， 40 healthy subjects who underwent physical examination at the same time were selected as the control group， and the blood routine indicators of the 3 groups were compared. Results The levels of HGB， MCV， MCH and MCHC in group A and group B were lower than those in the control group. The RDW level of group A and group B was higher than that of the control group. The RBC of group B was (4.78±0.79) 1012/L， RDW (0.20±0.02)%， HGB (94.29±6.58) g/L were higher than group A， group B RBC (4.78±0.79) 1012/L was higher than the control group， group A RBC (3.55±0.63) 1012/L was lower than the control group，the differences were statistically significant (P<0.05). Conclusion Blood routine test results can be used as a method to differentially diagnose iron deficiency anemia and globin-producing anemia.
, 百拇医药
Key words：Globin production barrier;Iron deficiency anemia;Blood routine test;Identification method
贫血(anemia)是临床中常见的血液疾病，常表现为脸色苍白、乏力、食欲不振、易疲倦等，原因为造血物质缺乏、造血功能障碍、红细胞破坏过多和大量出血等，以缺铁性贫血和珠蛋白生成障碍在临床中最为常见[1]。虽然缺铁性贫血和珠蛋白生成障碍性贫血同属于小细胞低色素性贫血，然而两者在病因、发病机制、治疗上截然不同。因此在临床需要对上述两种贫血类型进行准确诊断鉴别，从而为临床治疗提供可靠依据十分重要[2]。血常规检验是临床常用的检验方法，其操作简便，标本易得，结果直观，是很多疾病诊断常用的方法。本研究运用血常规检测方法及结果来鉴别诊断缺铁性贫血和珠蛋白生成障碍性贫血，对血常规鉴别诊断两者的临床效果进行分析。
1资料与方法
1.1一般资料 选择佳木斯市中医院2017年1月～2018年1月确诊收治的贫血患者80例。本研究已经过医院医学伦理委员会同意，所有研究对象均知情同意并签署知情同意书。按照贫血类型分为甲、乙组，其中甲组为缺铁性贫血患者38例，男16例，女22例;年龄19～63岁，平均年龄(38.91±5.12)岁;病程4个月～5年，平均病程(2.25±0.53)年; 乙组42例均为珠蛋白生成障碍性贫血患者，其中男19例，女23例，年龄19～57岁，平均年龄(38.76±4.21)岁; 病程3个月～6年，平均病程(2.04±0.76)年;另选择同期在本院中接受体检的健康者40例设为对照组，其中男24例，女16例;年龄20～65 岁，平均年龄(39.25±5.06)岁。, http://www.100md.com(吴云)