鼻腔扩容术对OSAHS的疗效及对咽部软腭长度的影响(1)
摘要：目的 探讨鼻腔扩容术对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的治疗效果及对咽部软腭长度的影响。方法 选取2016年10月～2017年12月我院收治的30例OSAHS患者，均行鼻腔擴容术治疗，比较手术前后睡眠呼吸暂停低通气指数(AHI)、最低动脉血氧饱和度(SaO2)、鼻阻力变化及软腭长度。结果 术后患者AHI为(26.89±20.73)次/h，低于术前的(48.32±17.64)次/h，最低SaO2水平为(90.24±7.40)%，高于术前的(80.59±8.42)%，差异有统计学意义(P<0.05)。术后患者鼻阻力、软腭长度分别为(0.30±0.12)Pa/(cm3·s)、(37.28±5.46)mm，均低于术前的(0.43±0.15)Pa/(cm3·s)、(45.68±7.30)mm，差异具有统计学意义(P<0.05)。结论 OSAHS患者采用鼻腔扩容术治疗，效果显著，可增加鼻腔有效通气，同时降低鼻阻力，改善软腭长度。
关键词：鼻腔扩容术;阻塞性睡眠呼吸暂停低通气综合征;咽部软腭长度;鼻阻力
中图分类号：R766.9 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.15.033
文章编号：1006-1959(2019)15-0104-02
Abstract：Objective To investigate the effect of nasal cavity expansion on the treatment of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and the length of pharyngeal soft palate.Methods 30 patients with OSAHS admitted to our hospital from October 2016 to December 2017 were treated with nasal dilatation. The sleep apnea hypopnea index (AHI) and the minimum arterial oxygen saturation (SaO2) were compared before and after surgery. Changes in nasal resistance and length of soft palate.Results The AHI of patients after operation was (26.89±20.73) times/h， which was lower than that of preoperative (48.32±17.64) times/h， and the lowest SaO2 level was (90.24±7.40)%， which was higher than that before operation (80.59±8.42)%， the difference was statistically significant (P<0.05). The postoperative nasal resistance and soft palate length were (0.30±0.12)Pa/(cm3·s) and (37.28±5.46)mm， respectively， which were lower than the preoperative (0.43±0.15)Pa/(cm3·s)，(45.68±7.30)mm， the difference was statistically significant (P<0.05).Conclusion Patients with OSAHS are treated with nasal dilatation. The effect is significant， which can increase the effective ventilation of the nasal cavity， reduce the nasal resistance and improve the length of soft palate.
Key words：Nasal expansion;Obstructive sleep apnea hypopnea syndrome;Pharyngeal soft palate length;Nasal resistance
阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome，OSAHS)指睡眠状态下上气道塌陷阻塞所导致的低通气及呼吸暂停[1]。OSAHS患者睡眠结构紊乱，通常伴有打鼾、注意力下不集中、血氧饱和度下降等症状，若未得到及时有效的治疗可引起冠心病、高血压、2型糖尿病等多种疾病，同时造成多器官功能损害。当前普遍认为，OSAHS是一种复杂的多因素疾病，鼻腔、咽部疾病、遗传、内分泌疾病、肥胖、肌肉神经支配异常等均与该病的发生密切相关。在临床实际工作中，应遵循重构上呼吸道、维持气道通畅、减轻呼吸紊乱原则对OSAHS患者进行治疗[2]。本文探讨鼻腔扩容术对OSAHS患者的治疗效果及对咽部软腭长度的影响，现报告如下。, 百拇医药(刘爽)
关键词：鼻腔扩容术;阻塞性睡眠呼吸暂停低通气综合征;咽部软腭长度;鼻阻力
中图分类号：R766.9 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.15.033
文章编号：1006-1959(2019)15-0104-02
Abstract：Objective To investigate the effect of nasal cavity expansion on the treatment of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and the length of pharyngeal soft palate.Methods 30 patients with OSAHS admitted to our hospital from October 2016 to December 2017 were treated with nasal dilatation. The sleep apnea hypopnea index (AHI) and the minimum arterial oxygen saturation (SaO2) were compared before and after surgery. Changes in nasal resistance and length of soft palate.Results The AHI of patients after operation was (26.89±20.73) times/h， which was lower than that of preoperative (48.32±17.64) times/h， and the lowest SaO2 level was (90.24±7.40)%， which was higher than that before operation (80.59±8.42)%， the difference was statistically significant (P<0.05). The postoperative nasal resistance and soft palate length were (0.30±0.12)Pa/(cm3·s) and (37.28±5.46)mm， respectively， which were lower than the preoperative (0.43±0.15)Pa/(cm3·s)，(45.68±7.30)mm， the difference was statistically significant (P<0.05).Conclusion Patients with OSAHS are treated with nasal dilatation. The effect is significant， which can increase the effective ventilation of the nasal cavity， reduce the nasal resistance and improve the length of soft palate.
Key words：Nasal expansion;Obstructive sleep apnea hypopnea syndrome;Pharyngeal soft palate length;Nasal resistance
阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome，OSAHS)指睡眠状态下上气道塌陷阻塞所导致的低通气及呼吸暂停[1]。OSAHS患者睡眠结构紊乱，通常伴有打鼾、注意力下不集中、血氧饱和度下降等症状，若未得到及时有效的治疗可引起冠心病、高血压、2型糖尿病等多种疾病，同时造成多器官功能损害。当前普遍认为，OSAHS是一种复杂的多因素疾病，鼻腔、咽部疾病、遗传、内分泌疾病、肥胖、肌肉神经支配异常等均与该病的发生密切相关。在临床实际工作中，应遵循重构上呼吸道、维持气道通畅、减轻呼吸紊乱原则对OSAHS患者进行治疗[2]。本文探讨鼻腔扩容术对OSAHS患者的治疗效果及对咽部软腭长度的影响，现报告如下。, 百拇医药(刘爽)