摘要：目的" 分析更年期综合征患者激素补充治疗效果不佳的影响因素。方法" 选取2022年1月-7月于我院行激素补充治疗的60例更年期综合征患者为研究对象，将治疗无效的30例患者设为无效组，另30例治疗有效者设为有效组，收集其基线资料，采用单因素及多因素分析更年期综合征患者激素补充治疗效果不佳的影响因素。结果" 单因素分析显示，有效组与无效组焦虑程度、依从性及合并症情况比较，差异有统计学意义(P<0.05)，而两组年龄、病程、BMI、发作次数、血清指标(E2、FSH、LH)比较，差异无统计学意义(P>0.05)。经Logistic回归分析显示，中、重度焦虑与依从性低下是更年期综合征患者HRT疗效不佳的独立危险因素(P<0.05)。结论" 更年期综合征患者的焦虑程度及依从性是引起激素补充治疗效果不佳的重要影响因素。

    关键词：更年期综合征；激素补充治疗；焦虑程度；依从性

    中图分类号：R711" " " " " " " " " " " " " " " " " "文献标识码：A" " " " " " " " " " " " " " " " "DOI：10.3969/j.issn.1006-1959.2023.17.025

    文章编号：1006-1959(2023)17-0127-03

    Analysis of Influencing Factors of Poor Effect of Hormone Replacement Therapy in Patients

    with Climacteric Syndrome

    DU Yu-dan，FANG Hong-hui，DENG Xia

    (Jiujiang Maternal and Child Health Hospital，Jiujiang 332001，Jiangxi，China)

    Abstract：Objective" To analyze the influencing factors of poor effect of hormone replacement therapy in patients with climacteric syndrome.Methods" A total of 60 patients with climacteric syndrome who underwent hormone replacement therapy in our hospital from January to July 2022 were selected as the research objects ......