梁雷锋 宋自晓 王仁生

    摘要：放射性口腔黏膜炎(RIOM)是头颈部肿瘤患者放疗过程中最常见的并发症之一，为早期剂量限制性毒性反应，对患者生活质量甚至肿瘤治疗效果产生不利影响。RIOM目前尚无预防和治疗的理想方案。本文就RIOM的流行病学、症状和分级标准、发病机制以及预防措施的进展做一综述，希望能为临床实践中处理RIOM提供参考。

    关键词：放射性口腔黏膜炎；放疗；头颈部肿瘤

    中图分类号：R781.5? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 文献标识码：A? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? DOI：10.3969/j.issn.1006-1959.2024.11.035

    文章编号：1006-1959(2024)11-0165-05

    Evaluation， Pathogenesis and Prevention of Radiation-induced Oral Mucositis

    Abstract：Radiation-induced oral mucositis (RIOM) is one of the most common complications in patients with head and neck cancer during radiotherapy. It is an early dose-limiting toxic reaction that adversely affects the quality of life of patients and the effect of tumor treatment. At present， there is no ideal scheme for the prevention and treatment of RIOM. This article reviews the epidemiology， symptoms and grading standards， pathogenesis and preventive measures of RIOM， hoping to provide reference for the treatment of RIOM in clinical practice. ......