摘要：肺癌是全球死亡率排行首位的恶性肿瘤，由于病情发展快，治疗手段有限，现阶段仅在早期才有较好的预后。许多肺癌筛查实验中已经证明，通过筛查提高早期肺癌检出率是降低所有人群肺癌死亡率的有效措施，早诊断、诊断准是关键。完善筛查策略、合理划分界定高危人群标准是实现早诊早治需要解决的重要课题，需要进一步发掘肺癌筛查技术中影像学、生物标志物、人工智能等筛查方法在临床诊断与风险评估的潜力。本文回顾肺癌筛查历史的关键节点，综合分析肺癌筛查现状与发展的持续研究，以探讨肺癌筛查计划的可行性问题。

    关键词：肺癌；早期筛查；高危人群；筛查技术；成本效益；筛查计划

    中图分类号：R734.2 " " " " " " " " " " " " " " " " 文献标识码：A " " " " " " " " " " " " " " " " DOI：10.3969/j.issn.1006-1959.2024.13.037

    文章编号：1006-1959(2024)13-0169-05

    Current Status and Development of Lung Cancer Screening

    HE Zong-lin1，LONG Jie-cun1，WANG Jia-sheng1，LAN Xiao-xi2，PENG Xu2，CAI Kai2

    (1.Graduate School of Guangxi University of Chinese Medicine，Nanning 530021，Guangxi，China;

    2.the First Affiliated Hospital of Guangxi University of Chinese Medicine/the First Clinical Medical College

    of Guangxi University of Chinese Medicine，Nanning 530021，Guangxi，China)

    Abstract：Lung cancer is the malignant tumor with the highest mortality rate in the world. Due to the rapid development of the disease and the limited treatment methods， it has a good prognosis only in the early stage. Many lung cancer screening experiments have proved that improving the detection rate of early lung cancer through screening is an effective measure to reduce the mortality rate of lung cancer in all populations. Early diagnosis and accurate diagnosis are the key. Improving screening strategies and rationally dividing and defining high-risk population standards are important issues to be solved in order to achieve early diagnosis and treatment. It is necessary to further explore the potential of imaging ......