摘要：头痛是一种原发性头痛障碍，通常表现为反复发作的中度至严重的头痛，已成为全球50岁以下患者的一个主要致残原因。偏头痛是多种遗传变异和环境危险因素共同作用的结果，B族维生素参与调节线粒体能量代谢和调节血管炎性反应。近年来研究发现B族维生素不足或缺乏(尤其是核黄素、叶酸、维生素B12)与偏头痛有关，且补充B族维生素可以改善偏头痛。本文就B族维生素与偏头痛的相关性进行综述，从而为其临床治疗提供参考。

    关键词：B族维生素；偏头痛；同型半胱氨酸；能量代谢

    中图分类号：R747.2" " " " " " " " " " " " " " " " " 文献标识码：A" " " " " " " " " " " " " " " " DOI：10.3969/j.issn.1006-1959.2024.14.038

    文章编号：1006-1959(2024)14-0179-05

    Research and Application Status of Correlation Between B Vitamins and Migraine

    ZHOU Shao-juan

    (Department of Medical Prevention Management，Nantong Center for Disease Control and Prevention，Nantong 226000，Jiangsu，China)

    Abstract：Migraine is a primary headache disorder， usually manifested as recurrent moderate to severe headache， which has become a major cause of disability in patients under the age of 50 worldwide. Migraine is the result of a combination of genetic variations and environmental risk factors. B vitamins are involved in regulating mitochondrial energy metabolism and regulating vascular inflammatory response. In recent years， studies have found that B vitamin hypovitaminosis or B vitamin deficiency (especially riboflavin ......