摘要：红细胞分布宽度(RDW)反映外周血红细胞体积大小的变异程度，异常的RDW提示红细胞生成障碍和生存周期的异常。近年来研究发现，RDW与高血压及动脉硬化程度密切相关，RDW水平升高可初步预测高血压和动脉硬化的发生发展、严重程度及不良预后，其相关机制可能与氧化应激、慢性炎症、红细胞稳定性与变形性、肾素-血管紧张素-醛固酮系统(RAAS)系统激活及交感神经活性亢进相关。本文旨在通过对RDW与高血压、动脉硬化的相关性及其可能的病理生理机制进行综述，探讨RDW评估高血压及动脉硬化发生风险及预后的临床意义和价值，以期为心脑血管疾病的早期诊疗及预后评价提供依据。

    关键词：RDW;高血压;动脉硬化

    中图分类号：R544.1; R543.1+2" " " " " " " " " " "文献标识码：A" " " " " " " " " " " " " " "DOI：10.3969/j.issn.1006-1959.2025.01.036

    文章编号：1006-1959(2025)01-0174-06

    Correlation Between RDW and Hypertension， Arteriosclerosis

    YANG Guangqiao， ZHANG Shiyi， DENG Jie

    (Department of General Practice， Yan'an Hospital Affiliated to Kunming Medical University， Kunming 650051， Yunnan， China)

    Abstract： Red blood cell distribution width (RDW) reflects the degree of variation of red blood cell volume in peripheral blood. Abnormal RDW indicates red blood cell generation disorder and abnormal life cycle. In recent years， studies have found that RDW is closely related to the degree of hypertension and arteriosclerosis. The increase of RDW level can preliminarily predict the occurrence ......