摘要：肝细胞癌患者早期常无明显症状，确诊时多为中晚期且预后差，这与肿瘤侵袭性强密切相关。术前准确评估肿瘤的侵袭性对肝癌患者治疗方案的制定至关重要，穿刺活检获取的信息有限，存在漏诊以及肿瘤破裂出血、播散的风险。影像组学能挖掘成大量像特征，更全面地反映肿瘤内部异质性，在肝脏肿瘤中应用广泛。随着影像组学的发展和完善，众多研究揭示了其在无创性评估肝细胞癌侵袭性方面的显著成果，旨在为临床提供一种更为精准有效的术前评估工具。本文系统梳理并综述近年来MRI影像组学在探索肝细胞癌侵袭性领域所取得的研究进展，以期准确评估肿瘤状态，便于临床进行制定精确、个性化的治疗策略。

    关键词：肝细胞癌；侵袭性；影像组学；磁共振成像

    中图分类号：R735.7" " " " " " " " " " " " " " " " 文献标识码：A" " " " " " " " " " " " " " " " "DOI：10.3969/j.issn.1006-1959.2025.06.033

    文章编号：1006-1959(2025)06-0173-06

    Research Progress of MRI Radiomics in the Invasiveness of Hepatocellular Carcinoma

    LI Na， ZHAO Dandan， XU Jingxing， LI Hong

    (Department of Radiology and Imaging， Affiliated Renhe Hospital of China Three Gorges University，

    Yichang 443000， Hubei， China)

    Abstract： Patients with hepatocellular carcinoma often have no obvious symptoms in the early stage， and most of them are in the middle and late stage at the time of diagnosis and have poor prognosis， which is closely related to the strong invasiveness of the tumor. Accurate preoperative assessment of tumor invasiveness is crucial for the formulation of treatment plans for patients with liver cancer. The information obtained by biopsy is limited ......