EffectofCEAandCA-199RatioasGastrointestinal TumorMarkers onthePrognosisof Colorectal Cancer

    HOUHuafangl，XIAYanqiu1，ZHANGZhe2，LEIXiao2 (The Second Department of Gastrointestinal Surgery，Department of Traditional Chinese Medicine， Affiliated Hospital of North Sichuan Medical College，Nanchong 637Ooo，Sichuan，China)

    Abstract：ObjectiveTostudytheefectofCEA/CA-199(EAR)ontheprogosisofcolorectalcancerpatientswithoralCEAandCA-199 expresioneslaof9oalisilCdeedall HospitalofNorthScanMedicalClgefroJauaryO4tJune16ereaalydretrospectivelyTherelatoshipetweepreatie peripherallodEAleveldlicalseharaceristisfloecalncedspactorogosrealdsultsder theROCcurveUCas588sugestingatERdagostisigificac.eutoffvueofOCurves.524.Thleveoas related to lymph node metastasis P=0 . 0 2 7 ， andtumor size (P=O.Ol6).Survival analysis showed that the overall survival rate of the low EAR group was lower than that of the high EAR group P=0 . 0 0 6 ) .Univariate COX analysis showed that lymph node metastasis ，distant metastasis P=0 . 0 0 1 ) (204 and EAR expression wereprognostic factors inpatientswithcolorectal cancer.Multivariate COXregressionanalysis showed that distant metastasis( and EAR expression( P=0 . 0 3 6 ) were independent prognostic factors affecting the prognosis of patients with colorectal cancer. ConclusionPreoperativeEcanbesedsefereceindeforthergosisfolocaerpatintsialEandCesio Key words：Colorectal cancer；CEA/CA-199；Prognosis ......