AReal-worldStudyofTislelizumabinthe TreatmentofPatients with Advanced Non-small Cell Lung Cancer

    HANHan，CHEN Yuchen，LIU Yang，RENFangfang，WANGXiyong (Oncology Department，Suzhou Hospitalof Anhui Medical University，Suzhou 234ooo，Anhui，China)

    Abstract：Oeiveecndefbiatofdalllungl MethodsFromJanuaryO2OtoOctober2O23，patientswithadvancedNSCLCtreatedwithtislelzumabinSuzhouHospitalofAnhuiMedical UniverstyweredsiliicalacedsftisldKaaeerddfor survivalanalydCseoodlsdfelsulAotfatiseudn PFS was 5.43(95%CI 3.84-7.03)months，the medianOSwas12.17(95%CE7.72-16.62)months，andtheORRand DCR were 3 6 . 8 4 % and 6 6 . 3 2 % ， respectively.Kaplan-Meier univariate analysis showed that metastasis siteand ECOG score were related to PFS ( Plt;0 . 0 5 ) ，while metastasis site，ECOG score and treatment line number were related to OS( .Multivariate analysis showed that intrapulmonary metastasis，distant metastasis，ECOG scoreandumberoftreamentlineswereindependentinfuencingfacorsofandintrapulmonarymelastasisECOGscoreadberf treatmentneepdtcorOeytlealdee reactionsignallsdldnli patients with advanced NSCLC. ......