阿卡波糖与达格列净治疗2型糖尿病的临床效果及药物不良反应分析

中图分类号:R587.1文献标识码:A
DOI:10.3969/j.issn.1006-1959.2025.12.029 文章编号:1006-1959(2025)12-0136-04
Analysis of Clinical Effect and Adverse DrugReactionsof Acarboseand Dapagliflozin intheTreatmentof Type2DiabetesMellitus
ZHU Jian
(DepartmentofPharmacy,Yanshan CountyHospitalofTraditionalChinese Medicine,Yanshan3345o,Jiangxi,China)
Abstract:ObjectieToalyethenicalefectnddversedgreactiosofcarboenddapaglfoinintetreatmentoftyabee mlitus(D.etosigdoerableto63sitdtdtsotitalofdioal ChineseMediefroJauarytoDceber3eredivideditoarboseoup31patints)nddapaglflingrou32patints)hc wertreatediabdalsiellccodosptelodcole bldcoee) fluctuationdeelefccusiGE)filfes)htsted reactionswerecomparedbetweethetogroupsesultsereasnsiificantdiereceinbloodglucosecomplancerateandldglucoe compliance time between the two groups( Pgt;0 0.05).The indexesofFPG,2hPBGand HbAlcinthetwo groups werelower than those before treatment ( Plt; 0.05),butthere wasnosignificant diffrence inFPG,2hPBGandHbAlc between the two groupsafter treatment( Pgt; 0.05). The values of MAGE and MODD in the dapagliflozin group were lower than those in the acarbose group( P lt;0.05).The bodyweight and waist circumference of the two groupsaftertreaeerelesstantoefotreantndodytandistfereeoftapalifoplesta those of the acarbose group( Plt;0.05 ).The incidence of adverse drug reactions in dapagliflozin group( 3.13% )was lower than that in acarbose group (19.35 % )( P? ......
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