中图分类号：R587.2；R692 文献标识码：A DOI：10.3969/j.issn.1006-1959.2025.14.011

    文章编号：1006-1959(2025)14-0067-04

    Abstract：ObectiveTvestgatethtsofLueangeeoctioolodcoseifaatoactodalfuctioatsi diabeticnepropathyethosFortyeanatsedolyividedintoopscudingatsinoalopdthaats werefed with high-fatsugardiet for4weeksand thenfasted for ^12h .The diabetic kidney disease (DKD) rat model was established by streptozotocin (STZ).The rats were divided into DKD model group，DKD + AICAR group，DKD +low -concentration Chinese medicine group，and |DKD+high- concentrationCinesemedicinegoup.TheoalgroupndteDKDmodelgouperegivenitrapeioealijectioofoalsalinetheKD + (20号 AICARgroupwasgivenintraperitonealinjectionofadenosine-phosphate-activatedkinase(AMPK)activatorAICAR3Omg/kg，the DKD+low- concentrationChineseedicingroupasivenlowoncentrationChineseedicinendteD+igoncetrtionCineseedicinegoua givenhighoraieedatscdelsiod)etid urea nitrogen (BUN) were analyzed by automatic analyzer.The expresson of inflammatory factors TNF- ?α∝ and IL-6 was detected.Results Compared with the DKD model group，the FBG level inthe DKD+high-concentration Chinese medicine group was decreased( Plt;0.01 ) ......