晚期鼻咽癌新辅助化疗序贯同步放化疗50例临床护理(1)
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摘 要 目的：探讨晚期鼻咽癌患者新辅助化疗序贯同步放化疗的护理干预方法及效果。方法：将100例晚期鼻咽癌患者随机分为常规组和干预组各50例，常规组行同步放化疗，给予常规护理；干预组行新辅助化疗序贯同步放化疗，并在常规护理基础上针对不良反应给予系统护理干预。比较两组不良反应发生情况，评价护理满意度。结果：干预组口腔黏膜不适、胃肠道不适、骨髓抑制、心理障碍、放射野皮肤反应发生率均低于常规组(P<0.05，P<0.01),而护理满意度高于常规组(P<0.01)。结论：对晚期鼻咽癌行新辅助化疗序贯同步放化疗患者，针对不良反应给予系统护理干预，可减轻不良反应发生率、提高护理满意度。
关键词 新辅助化疗序贯同步放化疗；鼻咽癌；晚期；护理干预
中图分类号：R473.73 文献标识码：A 文章编号：1006-7256(2011)15-0009-02
Clinical nursing care of 50 cases of advanced nasopharyngeal cancer treated with neoadjuvant
chemotherapy and sequentially concurrent radiotherapy and chemotherapy
Pan San-jiang, Ou Dong-ling, Huang Ju-hua, et al
(Bao'an District People's Hospital of Shenzhen Municipality, Shenzhen Guangdong 518101, China)
Abstract Objective: To explore the nursing intervention methods and its effect in the treatment of advanced nasopharyngeal cancer with neoadjuvant chemotherapy and sequentially concurrent radiotherapy and chemotherapy. Methods: 100 patients with advanced nasopharyngeal cancer were randomly divided into routine nursing group and intervention group (50 patients for each group). The patients in the routine nursing group received concurrent radiotherapy and chemotherapy and were given routine nursing care; the patients in the intervention group were treated with neoadjuvant chemotherapy and sequentially concurrent radiotherapy and chemotherapy and they were given systematic nursing intervention aiming at the adverse reactions and on the basis of the routine nursing care. The incidence of adverse reactions was compared between the two groups and the patient's satisfaction with nursing care was evaluated. Results: The incidence of oral discomfort, gastrointestinal discomfort, bone marrow suppression, mental disorders and radioactive dermoreaction was lower in the intervention group than that in the routine nursing group (P<0.05,P<0.01); the degree of patient's satisfaction with nursing care was higher in the intervention group than the routine nursing group (P<0 ......
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