护理干预对非糜烂性反流病患者生活质量的影响(1)
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摘 要 目的：探讨护理干预对非糜烂性反流病(NERD)患者生活质量的影响。方法：将40例NERD患者随机分成观察组和对照组各20例，对照组患者采用埃索美拉唑和多潘立酮等治疗，观察组在此基础上实行针对性的护理干预，采用Zung焦虑自评量表(SAS)和抑郁自评量表(SDS)、SF-36对两组进行评估。结果：两组患者SAS 、SDS得分、依从性、SF-36总分及各因子分比较有统计学差异(P<0.05，P<0.01)。结论:对NERD患者进行全面综合的护理干预，能改善患者的焦虑、抑郁状态，建立良好的生活方式和饮食习惯，提高NERD患者的生活质量。
关键词 非糜烂性反流病;生活质量;护理干预
中图分类号：R473.5 文献标识码：A 文章编号：1006-7256(2011)15-0015-03
Impact of nursing intervention on the quality of life of patients with non-erosive reflux disease
Lin Li-man, Yang Ting, Yang Qing-xiu, et al
(Affiliated Shenzhen Bao'an Hospital to Southern Medical University, Shenzhen Guangdong 518101, China)
Abstract Objective: To explore the impact of nursing intervention on the quality of life of patients with non-erosive reflux disease (NERD). Methods: 40 patients with NERD were randomly divided into observation group and control group (20 patients for each group). The patients were treated with Esomeprazole and Domperidone in the control group and the patients in the observation group were given the targeted nursing intervention based on the medication. Zung self-rating anxiety scale (SAS) and self-rating depression scale (SDS) and SF-36 were used to make an assessment of the patients in the two groups. Results: There were statistically significant differences in the comparison of SAS and SDS scores, compliance, total scores of SF-36 and the score of each factor between the two groups (P<0.05,P<0.01). Conclusion: The comprehensive nursing intervention applied to the patients with NERD can relieve the patient's anxiety and depression, help them establish a good lifestyle and diet habit and improve their quality of life.
Key words Non-erosive reflux disease; Quality of life; Nursing intervention
胃食管反流病(GERD)是指胃内容物反流入食管引起的不适症状或并发症，包括反流性食管炎(RE)、非糜烂性反流病(NERD)和Barrett食管。NERD是指具有不少于3个月的典型胃灼热和反流症状，内镜检查未见食管黏膜破损，国外流行病学调查资料报道，NERD占GERD的50%~70%[1]。2009年1月~2010年1月，我们对20例NERD患者在药物治疗的基础上，进行针对性的心理、认知、行为护理干预，取得满意效果。现报告如下。
1 资料与方法
1.1 临床资料 选择我院消化内科确诊为NERD患者40例，男14例，女26例。入选标准：年龄在18~76岁；有反酸、反流、胃灼热、胸骨后疼痛等典型表现，内镜检查食管远端无充血、糜烂或溃疡形成，诊断标准符合我国1999年烟台会议共识[2]；排除消化性溃疡，功能性营养不良，恶性肿瘤，严重心、肺、肝、肾、胆管、血液系统疾病，青光眼、哺乳期和妊娠期妇女。其中抑郁患者11例。随机分为对照组和观察组各20例，两组在性别、年龄、病情等方面比较差异无统计学意义(P>0.05)。
1.2 方法 两组患者均口服埃索美拉唑每次20 mg，2次/d,连续服用8周后改用每次20 mg，1次/d；多潘立酮每次10 mg,3次/d ......
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