张继红 张丽 孔世杰 曹赤 李京良

    【摘要】目的：分析在胎儿畸形产前诊断中，实时动态四维超声应用价值。方法：以在我院进行产前胎儿畸形筛查产妇为研究对象，均为单胎妊娠，所有产妇均进行二维超声与实时动态四维超声检查，以产后随访结果为金标准，分析上述两种检查方法对胎儿畸形诊断价值。结果：300例产妇共分娩300名胎儿，其中30例经证实为胎儿畸形，骨折畸形、肺部畸形、心脏畸形、颜面畸形以及神经系统畸形各占2例、4例、6例、8例、10例。二维超声共检出19例胎儿畸形，实时动态四维超声共检出28例胎儿畸形，组间差异有统计学意义(P<0.05)。以产后随访结果为金标准，二维超声诊断准确度为93.67%、敏感度为63.33%、特异度为97.04%；实时动态四维超声检查准确度为99.00%、敏感度为93.33%、特异度为99.63%。结论：在胎儿畸形产前诊断中，实时动态四维超声检查准确率高于二维超声，值得研究。

    【关键词】实时动态四维超声；二维超声；产前诊断；胎儿畸形

    Clinical significance of real-time four-dimensional ultrasound in prenatal diagnosis of fetal malformation

    ZHANG Jihong， ZHANG Li， KONG Shijie， CAO Chi， LI Jingliang

    Yellow River Hospital affiliated to Henan University of Science and Technology， Sanmenxia， Henan 472000， China

    【Abstract】Objective： To analyze the application value of real-time dynamic four-dimensional ultrasound in prenatal diagnosis of fetal malformation. Methods： All parturients who underwent prenatal fetal malformation screening in our hospital were singleton pregnancies. All parturients were examined by two-dimensional ultrasound and real-time dynamic four-dimensional ultrasound. Taking the postpartum followup results as the gold standard ......