张惠珠

    【摘要】目的：研究对于患有慢性特发性荨麻疹疾病采用药物联合治疗方案(复方甘草酸苷+枸地氯雷他定)的效果情况，明确其研究价值。方法：78例患有慢性特发性荨麻疹疾病的患者均是来自我院在2015年3月—2020年9月这一时期接收的，将患者根据随机抽签法进行分组，各39例，对照组仅是单独的口服枸地氯雷他定片治疗，研究组又添加口服复方甘草酸苷片治疗，对比两组的疗效。结果：与对照组治疗总有效率(79.49%)相比，研究组患者(94.87%)更高(P<0.05)；治疗后研究组的症状评分相比于对照组均有明显的减少(P<0.05)；治疗后研究组的IL-12与IFN-γ水平相比于对照组增长更加明显，而IL-4、IL-8及IgE水平相比于对照组降低程度更大(P<0.05)。结论：对于患有慢性特发性荨麻疹疾病采用药物联合治疗方案(复方甘草酸苷+枸地氯雷他定)可有效调节各细胞因子及抗体IgE水平，疗效确切，应用价值较高。

    【关键词】复方甘草酸苷；枸地氯雷他定；慢性特发性荨麻疹；症状评分；细胞因子

    Therapeutic effect of compound glycyrrhizin combined with desloratadine citrate in chronic idiopathic urticaria

    ZHANG Huizhu

    Tongguan County People’s Hospital of Weinan City， Weinan， Shaanxi 714399， China

    【Abstract】Objective： To study the effect of drug combination therapy (compound glycyrrhizin + medloratadine) on patients with chronic idiopathic urticaria and clarify its research value. Methods： 78 patients with chronic idiopathic urticaria were received from our hospital from March 2015 to September 2020. The patients were randomly divided into groups ......