HPV分型检测应用于宫颈癌或癌前病变筛查的效果
1资料与方法,2结果,3讨论
罗妹子 张镜明

【摘要】目的:研究HPV分型检测在宫颈癌或癌前病变筛查中的应用效果。方法:选取我院2018年4月—2023年3月间38例诊断意义不明的不典型鳞状细胞以上病变的病例,所有患者均进行HPV分型检测以及阴道镜下多点取材活检,以病理活检作为诊断宫颈癌或癌前病变的金标准,分析HPV分型检测在宫颈癌或癌前病变筛查中的应用效果。结果:与病理诊断结果对比发现,HPV分型检测的真阳性为25例,检出率为65.79%;灵敏度为92.59%,特异度为27.27%,假阴性率为7.41%,假阳性率为72.73%,诊断符合率为73.68%,阳性预测值为75.76%,阴性预测值为60.00%;HPV16型感染患者数为19例,和宫颈癌及癌前病变关系最为密切。结论:HPV分型检测对宫颈癌或癌前病变筛查而言,具有很好的临床推广和应用价值。
【关键词】宫颈癌;癌前病变;HPV分型检测;筛查
Effect of HPV typing test in screening cervical cancer or precancerous lesions
LUO Meizi, ZHANG Jingming
Dongguan Dongcheng Hospital, Dongguan, Guangdong 523000, China
【Abstract】Objective:To study the application effect of HPV typing test in screening cervical cancer or precancerous lesions. Methods:From April 2018 to March 2023, 38 cases of atypical squamous cell lesions with unknown diagnostic significance were selected in our hospital. All patients underwent HPV typing test and multi-point biopsy under colposcopy. Pathological biopsy was taken as the gold standard for diagnosis of cervical cancer or precancerous lesions ......
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