【摘要】目的：探究妊娠期肝内胆汁淤积症的临床特征及妊娠结局分析。方法：选取本院明确诊断的200例妊娠期肝内胆汁淤积症患者，选取时段2019年7月—2022年7月。随机数字表法分组，对照组与治疗组分别纳入100例。对照组单一熊去氧胆酸治疗，治疗组中药联合熊去氧胆酸治疗。比较观察两组患者治疗前后临床症状积分、实验室指标变化及妊娠结局。结果：治疗后两组瘙痒、疲劳、失眠症状积分均显著低于同组治疗前(P<0.05)；且治疗组较对照组显著更低(P<0.05)。治疗后两组CG、ALT、TBA均明显低于同组治疗前(P<0.05)；且治疗组较对照组显著更低(P<0.05)。在产后出血、早产儿发生率方面，治疗组较对照组显著下降(P<0.05)。结论：中药联合熊去氧胆酸治疗妊娠期肝内胆汁淤积症可有效减轻临床症状，改善肝功能，减少不良妊娠结局。

    【关键词】妊娠期；肝内胆汁淤积症；妊娠结局

    Clinical characteristics and pregnancy outcome analysis of intrahepatic cholestasis of pregnancy

    SHI Jinyun

    Obstetrics Department of Xinghua Maternal and Child Health Hospital， Xinghua， Jiangsu 225700， China

    【Abstract】Objective： To explore the clinical characteristics and pregnancy outcome analysis of intrahepatic cholestasis of pregnancy. Methods： 200 patients with intrahepatic cholestasis of pregnancy diagnosed in our hospital were selected from July 2019 to July 2022. Randomized number table grouping， with 100 cases included in the control group and 100 cases included in the treatment group. The control group was treated with Ursodeoxycholic acid alone ......