【摘要】目的：探究阿替普酶静脉溶栓治疗急性脑梗死的效果及对神经功能与生存质量的影响。方法：筛取2019年1月—2022年6月期间院内收治的共计90例急性脑梗死患者，按照随机数表法将患者分为两组，每组45例，对照组采用常规治疗，试验组采用阿替普酶静脉溶栓治疗。比较两组治疗效果。结果：与对照组相比，试验组治疗总有效率更高，P<0.05。试验组并发症发生率为6.67%，低于对照组的22.22%，P<0.05。治疗前，两组的NIHSS、SF-36及ADL评分比较差异不大，P>0.05；治疗后，试验组NIHSS评分低于对照组，SF-36及ADL评分高于对照组，P<0.05。结论：对急性脑梗死患者采用阿替普酶静脉溶栓治疗取得了良好效果，改善患者神经功能和生存质量，且能促进其日常生活活动能力的提升，值得推荐。

    【关键词】脑梗死；急性；阿替普酶；静脉溶栓；神经功能；生存质量

    The therapeutic effect of intravenous thrombolysis with alteplase on acute cerebral infarction and its impact on neurological function and quality of life

    ZHANG Jinlong， QIANG Man

    Qishan County Hospital， Baoji， Shaanxi 722400， China

    【Abstract】Objective：To explore the therapeutic effect of intravenous thrombolysis with alteplase on acute cerebral infarction，as well as its impact on neurological function and quality of life.Methods：A total of 90 patients with acute cerebral infarction admitted to the hospital from January 2019 to June 2022 were selected.The patients were divided into two groups using the random number table method ......