【摘要】目的：研究联合水化疗法配合心理干预对预防冠脉介入造影剂肾损伤的效果。方法：选取2021年7月—2021年12月开平市中心医院100例经皮冠状动脉介入治疗患者，按照组间基本特征匹配原则分为两组，各50例。对照组采用常规护理，实验组在对照组基础上联合水化疗法配合心理干预，比较两组护理效果。结果：干预前，两组SCr水平、β2-MG水平、SDS评分及SAS评分比较无统计学意义(P>0.05)；干预后，实验组的SCr水平、β2-MG水平、SDS评分及SAS评分均低于对照组，比较有统计学意义(P<0.05)。结论：针对冠脉介入造影剂肾损伤患者结合水化治疗和心理干预，可缓解患者负性情绪，提高心脏功能，防止造影剂引起肾脏损害，改善预后，值得临床推广应用。

    【关键词】水化疗法；心理干预；心脏功能；冠脉介入造影剂肾损伤；心理状态；临床效果

    基金名称：江门市卫生健康局科学技术研究项目《联合水化疗法配合心理干预对预防冠脉介入造影剂肾损伤的效果观察》(22A088)

    Observation on the effect of combined hydration therapy with psychological intervention on preventing renal injury caused by coronary intervention contrast agent

    LAO Chunhuan， WEN Guizhen， ZHANG Qilian

    Department of Cardiovascular Medicine， Kaiping Central Hospital， Jiangmen， Guangdong 529300， China

    【Abstract】Objective：To study the effect of hydration therapy combined with psychological intervention on the prevention of renal injury caused by coronary intervention contrast agent.Methods：100 patients with percutaneous coronary intervention in Kaiping Central Hospital from July 2021 to December 2021 were selected and divided into two groups according to the principle of matching basic features between groups ......