基于网络药理学与分子对接探讨舒泌通胶囊“异病同治”治疗良性前列腺增生和慢性前列腺炎的作用机制*
Exploration of Action Mechanism of Shubitong Capsule in the Strategy of the Same Treatment for Different Diseases in the Treatment of Benign Prostatic Hyperplasia and Chronic Prostatitis Based on Network Pharmacology and Molecular DockingJIAO Xu-ran1 ,LI Yan-feng1,2 , ZHANG Chun - he2
(1.YunanUesitfdolseedinOstclcalCfif Traditionleistfledalclsalfdlec 【Abstract】Objective:To explore the mechanism of action of Shubitong Capsule in the treatment ofbenign prostatic hyperplasia(BPH)and chronic prostatitis(CP)by using network pharmacology methods. Methods: The components and action targets of Shubitong Capsule were obtained through the TCMSP database.The action targets of CP and BPH were obtained through the GeneCards,OMIM,PharmGkb and DrugBank databases.The Venn diagram of the common effective targets of Shubitong Capsule in the treatment of CP and BPH was drawn through the Lianchuan Biological Cloud platform.The protein- protein interaction (PPI) network of common genes was constructed through the STRING database.The core targets were screened out through the Cytoscape software ......
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