玫瑰糠疹治疗效果分析(1)
doi：10.3969/j.issn.1007-614x.2014.3.54
摘 要 目的：探讨复方樟脑乳膏、复方青黛胶囊、氯雷他定联合治疗玫瑰糠疹的临床疗效。方法：收治玫瑰糠疹患者80例，随机分成对照组和观察组各40例。对照组单纯给予泛昔洛韦0.3g/次，2次/日，观察组在对照组的基础上加用复方青黛胶囊，4粒/次，3次/日，氯雷他定10mg/日，复方樟脑乳膏外用，涂抹3次/日，连续治疗7天。结果：观察组痊愈36例，显效4例，总有效率100.0%；对照组痊愈24例，显效6例，好转2例，无效8例，总有效率80.0%，两组比较差异有统计学意义(P<0.05)。结论：复方樟脑乳膏、复方青黛胶囊、氯雷他定联合治疗玫瑰糠疹疗效显著。
关键词 复方樟脑乳膏 复方青黛胶囊 氯雷他定 玫瑰糠疹
Analysis of treatment effect of pityriasis rosea
Xue Weijie，Guo Chenhui
Yuanhui District Maternal and Child Health Hospital of Luohe City，Henan Province，462000
Abstract Objective：To investigate the clinical efficacy of Compound Camphor Cream，compound Qingdai capsule and loratadine combination treatment of pityriasis rosea.Methods：We selected 80 cases of patients with pityriasis rosea from 2012 July to 2013 September，and these patients were randomly divided into the observation group and the control group with 40 cases in each.The control group was only given famciclovir with 0.3g/time，2 times/day.The observation group was treated with compound Qingdai capsule in 4 capsules each time，3 times/day，loratadine 10mg/day and Compound Camphor Cream external used in 3 times/day.Period of treatment was 7 days.Results：36 cases were cured and 4 cases were markedly effective in observation group，and the total effective rate was 100%.In the control group，24 cases were cured，6 cases markedly effective，2 cases improved，8 cases ineffective，and the total efficiency was 80%.The difference between the two groups was significant(P<0.05).Conclusion：The clinical efficacy of Compound Camphor Cream， compound Qingdai capsule and loratadine combination treatment of pityriasis rosea was significant，and it is worth spreading.
Key words Compound Camphor Cream；Compound Qingdai capsule；Loratadine；Pityriasis rosea
玫瑰糠疹(PR)是一种由各种因素引起急性的、自限性的炎症性皮肤病[1]，多发生在15～48岁[2]，由于病情迁延时间较长，给患者带来较大痛苦和心理压力。近年来，我们采用复方樟脑乳膏、复方青黛胶囊、氯雷他定联合治疗取得了较好的临床效果，现报告如下。
资料与方法
2012年7月-2013年9月收治玫瑰糠疹患者80例，男30例(37.5%)，女50例(62.5%)，男女之比0.6：1，年龄16～47岁，平均26.6岁。随机分成对照组和观察组各40例，两组在年龄、性别、玫瑰糠疹发生部位和面积等方面差异无统计学意义。
方法：对照组单纯给予泛昔洛韦0.3g/次，2次/日，观察组在对照组的基础上加用复方青黛胶囊，4粒/次，3次/日，氯雷他定10mg/日，复方樟脑乳膏外用，涂抹3次/日，连续治疗7天。
结 果
两组临床疗效比较：观察组痊愈36例，显效4例，总有效率100.0%，对照组痊愈24例，显效6例，好转2例，无效8例，总有效率80.0%，两组比较差异有统计学意义(P<0.05)，见表1。
讨 论
玫瑰糠疹是一种常见的自限性炎症性皮肤病，发病可能与病毒感染有关[3]，但未得到证实。表现以椭圆形玫瑰红色斑疹、覆有糠状鳞屑、好发于躯干和四肢近端为特征[4]。本病春秋季节好发，多见于青少年，一般4～8周可自行痊愈，很少复发，但少数患者病情迁延难愈[5]。主要表现：皮损为椭圆形或圆形玫瑰色斑疹，其长轴与皮纹走向一致，有的皮损呈环状，表面覆有糠状鳞屑；母斑：初起的单个较大损害；子斑：多量，甲盖大小斑疹，好发于躯干和四肢近端，散在分布；自觉不同程度的瘙痒；部分患者伴有全身不适、头痛、咽痛等上呼吸道感染症状。, http://www.100md.com(薛伟杰 郭晨晖)
摘 要 目的：探讨复方樟脑乳膏、复方青黛胶囊、氯雷他定联合治疗玫瑰糠疹的临床疗效。方法：收治玫瑰糠疹患者80例，随机分成对照组和观察组各40例。对照组单纯给予泛昔洛韦0.3g/次，2次/日，观察组在对照组的基础上加用复方青黛胶囊，4粒/次，3次/日，氯雷他定10mg/日，复方樟脑乳膏外用，涂抹3次/日，连续治疗7天。结果：观察组痊愈36例，显效4例，总有效率100.0%；对照组痊愈24例，显效6例，好转2例，无效8例，总有效率80.0%，两组比较差异有统计学意义(P<0.05)。结论：复方樟脑乳膏、复方青黛胶囊、氯雷他定联合治疗玫瑰糠疹疗效显著。
关键词 复方樟脑乳膏 复方青黛胶囊 氯雷他定 玫瑰糠疹
Analysis of treatment effect of pityriasis rosea
Xue Weijie，Guo Chenhui
Yuanhui District Maternal and Child Health Hospital of Luohe City，Henan Province，462000
Abstract Objective：To investigate the clinical efficacy of Compound Camphor Cream，compound Qingdai capsule and loratadine combination treatment of pityriasis rosea.Methods：We selected 80 cases of patients with pityriasis rosea from 2012 July to 2013 September，and these patients were randomly divided into the observation group and the control group with 40 cases in each.The control group was only given famciclovir with 0.3g/time，2 times/day.The observation group was treated with compound Qingdai capsule in 4 capsules each time，3 times/day，loratadine 10mg/day and Compound Camphor Cream external used in 3 times/day.Period of treatment was 7 days.Results：36 cases were cured and 4 cases were markedly effective in observation group，and the total effective rate was 100%.In the control group，24 cases were cured，6 cases markedly effective，2 cases improved，8 cases ineffective，and the total efficiency was 80%.The difference between the two groups was significant(P<0.05).Conclusion：The clinical efficacy of Compound Camphor Cream， compound Qingdai capsule and loratadine combination treatment of pityriasis rosea was significant，and it is worth spreading.
Key words Compound Camphor Cream；Compound Qingdai capsule；Loratadine；Pityriasis rosea
玫瑰糠疹(PR)是一种由各种因素引起急性的、自限性的炎症性皮肤病[1]，多发生在15～48岁[2]，由于病情迁延时间较长，给患者带来较大痛苦和心理压力。近年来，我们采用复方樟脑乳膏、复方青黛胶囊、氯雷他定联合治疗取得了较好的临床效果，现报告如下。
资料与方法
2012年7月-2013年9月收治玫瑰糠疹患者80例，男30例(37.5%)，女50例(62.5%)，男女之比0.6：1，年龄16～47岁，平均26.6岁。随机分成对照组和观察组各40例，两组在年龄、性别、玫瑰糠疹发生部位和面积等方面差异无统计学意义。
方法：对照组单纯给予泛昔洛韦0.3g/次，2次/日，观察组在对照组的基础上加用复方青黛胶囊，4粒/次，3次/日，氯雷他定10mg/日，复方樟脑乳膏外用，涂抹3次/日，连续治疗7天。
结 果
两组临床疗效比较：观察组痊愈36例，显效4例，总有效率100.0%，对照组痊愈24例，显效6例，好转2例，无效8例，总有效率80.0%，两组比较差异有统计学意义(P<0.05)，见表1。
讨 论
玫瑰糠疹是一种常见的自限性炎症性皮肤病，发病可能与病毒感染有关[3]，但未得到证实。表现以椭圆形玫瑰红色斑疹、覆有糠状鳞屑、好发于躯干和四肢近端为特征[4]。本病春秋季节好发，多见于青少年，一般4～8周可自行痊愈，很少复发，但少数患者病情迁延难愈[5]。主要表现：皮损为椭圆形或圆形玫瑰色斑疹，其长轴与皮纹走向一致，有的皮损呈环状，表面覆有糠状鳞屑；母斑：初起的单个较大损害；子斑：多量，甲盖大小斑疹，好发于躯干和四肢近端，散在分布；自觉不同程度的瘙痒；部分患者伴有全身不适、头痛、咽痛等上呼吸道感染症状。, http://www.100md.com(薛伟杰 郭晨晖)
参见：首页 > 医疗版 > 疾病专题 > 皮肤科 > 丘疹鳞屑性皮肤病 > 玫瑰糠疹