β—内酰胺类抗生素联合孟鲁司特钠片治疗烧伤后肺部感染的临床疗效(1)
doi：10.3969/j.issn.1007-614x.2014.4.20
摘 要 目的：研究并探讨采用β-内酰胺类抗生素联合孟鲁司特钠片治疗烧伤后肺部感染的临床疗效。方法：收治烧伤后肺部感染患者40例，将其随机分为对照组与观察组，各20例，对照组采用β-内酰胺类抗生素进行治疗，观察组采用β-内酰胺类抗生素联合孟鲁司特钠片进行治疗，经过一段时间的治疗后，对患者的病情演变以及预后症状进行观察，并比较分析。结果：观察组采用两种药物联合使用的效果明显优于对照组采用的单种药物治疗，组间比较差异具有统计学意义(P<0.05)。结论：采用β-内酰胺类抗生素联合孟鲁司特钠片治疗烧伤后肺部感染患者的临床效果较好，能够明显缓解病症发展，减轻患者的痛苦。
关键词 β-内酰胺类抗生素 孟鲁司特钠片 肺部感染 疗效观察
Clinical efficacy of bete lactam antibiotics combined with montelukast sodium tablets in the treatment lung infection after burn
Jin Lujia
The medicine agent department of people's hospital in Jiaozuo City，Henan Province，454002
Abstract Objective：Clinical research and explore the use of beta lactam antibiotics combined with montelukast sodium tablets in the treatment of pulmonary infection after burn.Methods：To admit 40 cases of patients with pulmonary infection after burn from February 2010 to February 2012，they were randomly divided into control group and observation group，each with 20 cases，the control group was treated with beta lactam antibiotic treatment，the observation group were treated with beta lactam antibiotics combined montelukast sodium tablets treatment，after a period of treatment，observation and comparison analysis of disease evolution and prognosis.Results：The observation group were treated by combining use of the two drugs was better than the control were treated by the single drug therapy，there were significant differences between the compared group(P<0.05).Conclusion：The clinical effect of using beta lactam antibiotics combined with montelukast sodium tablets in the treatment of pulmonary infection after burn is better，can significantly alleviate the symptoms，reduce the pain of patients，it is worth to popularize application.
Key words Beta lactam antibiotics；Montelukast sodium tablets；Pulmonary infection；Curative effect observation
烧伤后肺部感染是烧伤后较为常见的内脏并发症，发病后会伴随多项炎性反应，烧伤后发病率33%～40%[1]。患者的临床表现多为咳嗽、咳痰，不但痰量有所增加，且会出现较多脓性痰，同时伴有发热、呼吸困难等症状。研究表明，细菌的破坏作用和机体自身过度的炎性反应是导致烧伤后肺部感染的重要原因。临床治疗显示孟鲁司特钠片具有较强的抑制炎性反应作用。本次研究，笔者对我院部分烧伤后肺部感染患者采用β-内酰胺类抗生素联合孟鲁司特钠片进行治疗，效果较好。现将部分研究资料整理报告如下。
资料与方法
2010年2月-2012年2月收治烧伤后肺部感染患者40例，男22例，女18例，患者年龄35～52岁，平均(44.2±3.5)岁，所有患者入院时均有一定程度的发热、咳嗽、畏寒以及痰液较多等症状。研究在征得患者及其家属同意的情况下开展，将所有患者随机分为对照组与观察组两组，每组各20例。统计学对比两组年龄、性别、入院时间以及病理状况差异无统计学意义(P>0.05)。
治疗方法：入院治疗后两组均进行一定的常规治疗，对照组采用β-内酰胺类抗生素进行治疗，观察组在治疗组的基础上增加采用孟鲁司特钠片进行治疗，孟鲁司特钠片口服10mg/日，两组的日常生活方式无任何改变。
观察指标：研究对所有患者的发热、咳嗽、畏寒以及痰液等情况进行监测，观察记录所有患者的临床痊愈时间。, 百拇医药(靳露佳)
摘 要 目的：研究并探讨采用β-内酰胺类抗生素联合孟鲁司特钠片治疗烧伤后肺部感染的临床疗效。方法：收治烧伤后肺部感染患者40例，将其随机分为对照组与观察组，各20例，对照组采用β-内酰胺类抗生素进行治疗，观察组采用β-内酰胺类抗生素联合孟鲁司特钠片进行治疗，经过一段时间的治疗后，对患者的病情演变以及预后症状进行观察，并比较分析。结果：观察组采用两种药物联合使用的效果明显优于对照组采用的单种药物治疗，组间比较差异具有统计学意义(P<0.05)。结论：采用β-内酰胺类抗生素联合孟鲁司特钠片治疗烧伤后肺部感染患者的临床效果较好，能够明显缓解病症发展，减轻患者的痛苦。
关键词 β-内酰胺类抗生素 孟鲁司特钠片 肺部感染 疗效观察
Clinical efficacy of bete lactam antibiotics combined with montelukast sodium tablets in the treatment lung infection after burn
Jin Lujia
The medicine agent department of people's hospital in Jiaozuo City，Henan Province，454002
Abstract Objective：Clinical research and explore the use of beta lactam antibiotics combined with montelukast sodium tablets in the treatment of pulmonary infection after burn.Methods：To admit 40 cases of patients with pulmonary infection after burn from February 2010 to February 2012，they were randomly divided into control group and observation group，each with 20 cases，the control group was treated with beta lactam antibiotic treatment，the observation group were treated with beta lactam antibiotics combined montelukast sodium tablets treatment，after a period of treatment，observation and comparison analysis of disease evolution and prognosis.Results：The observation group were treated by combining use of the two drugs was better than the control were treated by the single drug therapy，there were significant differences between the compared group(P<0.05).Conclusion：The clinical effect of using beta lactam antibiotics combined with montelukast sodium tablets in the treatment of pulmonary infection after burn is better，can significantly alleviate the symptoms，reduce the pain of patients，it is worth to popularize application.
Key words Beta lactam antibiotics；Montelukast sodium tablets；Pulmonary infection；Curative effect observation
烧伤后肺部感染是烧伤后较为常见的内脏并发症，发病后会伴随多项炎性反应，烧伤后发病率33%～40%[1]。患者的临床表现多为咳嗽、咳痰，不但痰量有所增加，且会出现较多脓性痰，同时伴有发热、呼吸困难等症状。研究表明，细菌的破坏作用和机体自身过度的炎性反应是导致烧伤后肺部感染的重要原因。临床治疗显示孟鲁司特钠片具有较强的抑制炎性反应作用。本次研究，笔者对我院部分烧伤后肺部感染患者采用β-内酰胺类抗生素联合孟鲁司特钠片进行治疗，效果较好。现将部分研究资料整理报告如下。
资料与方法
2010年2月-2012年2月收治烧伤后肺部感染患者40例，男22例，女18例，患者年龄35～52岁，平均(44.2±3.5)岁，所有患者入院时均有一定程度的发热、咳嗽、畏寒以及痰液较多等症状。研究在征得患者及其家属同意的情况下开展，将所有患者随机分为对照组与观察组两组，每组各20例。统计学对比两组年龄、性别、入院时间以及病理状况差异无统计学意义(P>0.05)。
治疗方法：入院治疗后两组均进行一定的常规治疗，对照组采用β-内酰胺类抗生素进行治疗，观察组在治疗组的基础上增加采用孟鲁司特钠片进行治疗，孟鲁司特钠片口服10mg/日，两组的日常生活方式无任何改变。
观察指标：研究对所有患者的发热、咳嗽、畏寒以及痰液等情况进行监测，观察记录所有患者的临床痊愈时间。, 百拇医药(靳露佳)
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