小青龙汤联合西药治疗感冒后咳嗽31例临床观察(1)
【摘 要】 目的：观察小青龙汤联合西药治疗感冒后咳嗽的临床疗效。方法：选取感冒后咳嗽患者61例，随机分为两组，对照组应用阿莫西林、盐酸氨溴索治疗，研究组联合应用小青龙汤治疗，对比两组症状评分及炎性因子变化情况。结果：治疗前两组的咳嗽积分无统计学差异(P>0.05)，治疗后研究组显著低于对照组(P<0.05)；治疗前两组的中医症候积分无统计学差异(P>0.05)，治疗后研究组显著低于对照组(P<0.05)；治疗前两组的PCT无统计学差异(P>0.05)，治疗后研究组显著低于对照组(P<0.05)；研究组咳嗽缓解时间、消失时间以及肺部啰音消失时间与对照组相比，差异具有统计学意义(P<0.05)。结论：感冒后咳嗽患者应用小青龙汤联合西药治疗，有利于提高治疗效果，改善患者咳嗽症状评分以及中医症候评分，降低患者炎性因子水平，值得临床推广应用。
【关键词】 感冒后咳嗽；小青龙汤；阿莫西林
【中图分类号】R254 【文献标志码】 A 【文章编号】1007-8517(2018)10-0062-04
Abstract：Objective To observe the clinical effect of Xiaoqinglong Decoction Combined with Western Medicine on cough after cold.Methods 61 patients with cold cough were randomly divided into two groups.The control group was treated with amoxicillin， and the study group was treated with Xiao Qing long decoction.The symptom score and inflammatory factors were compared between the two groups.Results Two groups of patients before treatment of cough scores had no significant difference (P>0.05)， the research group after treatment was significantly lower than the control group (P<0.05)； TCM syndrome score of the two groups of patients before treatment had no significant difference (P>0.05)， the research group after treatment was significantly lower than the control group (P<0.05)； two PCT group of patients before treatment had no significant difference (P>0.05)， the research group after treatment was significantly lower than the control group (P<0.05)； the study group cough relief time， the disappearance time， pulmonary rales disappeared time compared with the control group， there is significant difference (P<0.05).Conclusion The application of Xiao qing long Decoction Combined with Western Medicine
in the treatment of cough after cold can improve the treatment effect， improve the cough symptom score and TCM symptom score， reduce the level of inflammatory factors in patients， and should be popularized in clinical practice.
Keywords：Post Cold Cough；Xiaoqinglong Decoction； Amoxicillin
感冒后咳嗽原称感染后咳嗽(PIC)，是指一系列急性期症状，如发热、呼吸道感染等症状消失后，咳嗽现象依旧没有缓解，并且持续时间长达3～8周[1]。呼吸道感染后，一般呈现的并发症有干咳或咳少量白色黏性痰、喉痒，C-反应蛋白、胸片、血常规均显示无异常。本病常呈自限性，即经过一段时间便可自行缓解或给予经验性治疗可痊愈。大部分學者认为本病的发病机制与气道上皮损伤、炎症和神经因素、气道高反应性等有关。而频繁剧烈的咳嗽严重影响患者的生活、学习和工作。笔者对收治的门诊及住院患者使用小青龙汤联合西药治疗，效果较好，现报道如下。
1 资料与方法
1.1 一般资料 选取2015年10月至2017年10月我院收治的门诊及住院患者61例，分为研究组和对照组。纳入标准：①由普通感冒引发的咳嗽，一般干咳或咳少量白痰；②病程长达3～8周或以上；③支气管激发试验呈阴性，肺通气功能正常；④胸部X线/CT检查无异常；⑤年龄20～56岁；⑥中医辨证为风寒，即咽痒气急，咳嗽声重，咳痰清稀，舌质淡且苔薄白，脉浮或紧。诊断标准：参考中华医学会《咳嗽的诊断以及治疗指南(2009版)》[2]制定。排除标准：①既往有慢性阻塞性肺病、支气管哮喘等慢性呼吸系统疾病史；②既往有慢性充血性心力衰竭病史或合并其他系统严重疾病的原发病者；③近1个月服用过卡托普利、依那普利等ACEI类药物；④平时有胃痛、反酸或鼻塞流清涕等症状；⑤体温超过37.3℃者；⑦有精神疾病，即不能配合研究的患者；⑧处于妊娠期及准备妊娠或哺乳期的妇女。所有均知情同意本研究，并经过医院伦理委员会批准。, 百拇医药(管奕婷)
【关键词】 感冒后咳嗽；小青龙汤；阿莫西林
【中图分类号】R254 【文献标志码】 A 【文章编号】1007-8517(2018)10-0062-04
Abstract：Objective To observe the clinical effect of Xiaoqinglong Decoction Combined with Western Medicine on cough after cold.Methods 61 patients with cold cough were randomly divided into two groups.The control group was treated with amoxicillin， and the study group was treated with Xiao Qing long decoction.The symptom score and inflammatory factors were compared between the two groups.Results Two groups of patients before treatment of cough scores had no significant difference (P>0.05)， the research group after treatment was significantly lower than the control group (P<0.05)； TCM syndrome score of the two groups of patients before treatment had no significant difference (P>0.05)， the research group after treatment was significantly lower than the control group (P<0.05)； two PCT group of patients before treatment had no significant difference (P>0.05)， the research group after treatment was significantly lower than the control group (P<0.05)； the study group cough relief time， the disappearance time， pulmonary rales disappeared time compared with the control group， there is significant difference (P<0.05).Conclusion The application of Xiao qing long Decoction Combined with Western Medicine
in the treatment of cough after cold can improve the treatment effect， improve the cough symptom score and TCM symptom score， reduce the level of inflammatory factors in patients， and should be popularized in clinical practice.
Keywords：Post Cold Cough；Xiaoqinglong Decoction； Amoxicillin
感冒后咳嗽原称感染后咳嗽(PIC)，是指一系列急性期症状，如发热、呼吸道感染等症状消失后，咳嗽现象依旧没有缓解，并且持续时间长达3～8周[1]。呼吸道感染后，一般呈现的并发症有干咳或咳少量白色黏性痰、喉痒，C-反应蛋白、胸片、血常规均显示无异常。本病常呈自限性，即经过一段时间便可自行缓解或给予经验性治疗可痊愈。大部分學者认为本病的发病机制与气道上皮损伤、炎症和神经因素、气道高反应性等有关。而频繁剧烈的咳嗽严重影响患者的生活、学习和工作。笔者对收治的门诊及住院患者使用小青龙汤联合西药治疗，效果较好，现报道如下。
1 资料与方法
1.1 一般资料 选取2015年10月至2017年10月我院收治的门诊及住院患者61例，分为研究组和对照组。纳入标准：①由普通感冒引发的咳嗽，一般干咳或咳少量白痰；②病程长达3～8周或以上；③支气管激发试验呈阴性，肺通气功能正常；④胸部X线/CT检查无异常；⑤年龄20～56岁；⑥中医辨证为风寒，即咽痒气急，咳嗽声重，咳痰清稀，舌质淡且苔薄白，脉浮或紧。诊断标准：参考中华医学会《咳嗽的诊断以及治疗指南(2009版)》[2]制定。排除标准：①既往有慢性阻塞性肺病、支气管哮喘等慢性呼吸系统疾病史；②既往有慢性充血性心力衰竭病史或合并其他系统严重疾病的原发病者；③近1个月服用过卡托普利、依那普利等ACEI类药物；④平时有胃痛、反酸或鼻塞流清涕等症状；⑤体温超过37.3℃者；⑦有精神疾病，即不能配合研究的患者；⑧处于妊娠期及准备妊娠或哺乳期的妇女。所有均知情同意本研究，并经过医院伦理委员会批准。, 百拇医药(管奕婷)