基于数据挖掘的《证治汇补》治疗脾胃病用药规律研究(1)
【摘 要】 目的：基于数据挖掘研究《证治汇补》治疗脾胃病的用药规律，以期为中医治疗脾胃病提供依据。方法：运用中医传承辅助平台V2.5软件对《证治汇补》中治疗脾胃病的有效方剂进行性味归经分布、频次统计、组方规律、核心组合、新方的分析。结果：共收集有效方剂137首，涉及中药159味，使用频次≥10的药物25味，以性温、味辛、归脾经类药物最多;支持度个数设置为18，置信数为0.6，得到常用药对及组合15个;基于软件复杂熵层次聚类方法，得到用于新方聚类的核心组合32组，聚合成新方16首。结论：《证治汇补》中治疗脾胃病以温补脾阳为主，用药方面以辛温药升阳行气为主，辅以甘性药滋补和中、调和药性。
【关键词】 李用粹;《证治汇补》;中医传承辅助平台;脾胃病;用药规律
【中图分类号】R256.3 【文献标志码】 A 【文章编号】1007-8517(2020)4-0005-04
Study on the Rule of Drugs for Treating Spleen and Stomach Diseases Based on Data Mining in Zheng Zhi Hui Bu
WANG jiarui1 YU bin1，2
1.Hunan University of Chinese Medicine，Changsha 410000，China;2.Department of Spleen and Gastroenterology，the First Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410000，China
Abstract：Objective To study the rule of treatment of spleen and stomach diseases based on data mining in Zheng Zhi Hui Bu，in order to provide a basis for Chinese medicine treatment of spleen and stomach diseases.Methods The effective prescription of spleen and stomach disease in the treatment of spleen and stomach disease in the treatment of spleen and stomach disease was carried out by using the V2.5 software of TCM inheritance platform to analyze the distribution of sexual taste，frequency statistics，prescription law，core combination and new prescription.Results A total of 137 effective prescriptions were collected，involving 159 flavors of traditional Chinese medicine.25 drugs with frequency ≥10 were used，and the most common drugs were wen，xin and spleen.The number of support was set to 18 and the confidence was 0.6.15 common drug pairs and combinations were obtained; based on the software complex entropy hierarchical clustering method，32 core groups for clustering of new parties were obtained，and 16 new parties were aggregated.Conclusion The treatment of spleen and stomach disease in the treatment of spleen and stomach disease is mainly based on warming spleen and yang.In terms of medication，Xinwen medicine is mainly used for yang qi，supplemented by sweet medicine to nourish and neutralize medicinal properties.
Keywords：Li Yongcui;《Zheng Zhi Hui Bu》;Chinese Medicine Inheritance Auxiliary Platform;Spleen and Stomach Diseases;Medication Rule
《證治汇补》乃清代医学家李用粹的代表著作。李用粹，字修之，号惺庵，明末清初人，其幼承家学，博览医书，晚年博采轩歧以来诸书，条贯辨析，标其举要，集为《证治汇补》[1]。《证治汇补》共8卷，分为提纲、内因、外体、上窍、胸膈、腹胁、腰膝及下窍8门，其中包括内科、杂病82类病症，每症中含有病因、外候、条目、辨证、脉象、治法、劫法、用药、附证及方剂。每项内均“集古人书而汇集之，删其繁而存其要，补其缺而正其偏”，故名之为《证治汇补》[1]。可以说《证治汇补》是一部中医临床工作者的必备参考书。笔者运用数据挖掘的方式，通过中医传承辅助平台V 2.5软件分析《证治汇补》中治疗脾胃病的用药规律，以期为中医治疗脾胃病提供依据。, 百拇医药(王嘉芮 喻斌)
【关键词】 李用粹;《证治汇补》;中医传承辅助平台;脾胃病;用药规律
【中图分类号】R256.3 【文献标志码】 A 【文章编号】1007-8517(2020)4-0005-04
Study on the Rule of Drugs for Treating Spleen and Stomach Diseases Based on Data Mining in Zheng Zhi Hui Bu
WANG jiarui1 YU bin1，2
1.Hunan University of Chinese Medicine，Changsha 410000，China;2.Department of Spleen and Gastroenterology，the First Affiliated Hospital of Hunan University of Chinese Medicine，Changsha 410000，China
Abstract：Objective To study the rule of treatment of spleen and stomach diseases based on data mining in Zheng Zhi Hui Bu，in order to provide a basis for Chinese medicine treatment of spleen and stomach diseases.Methods The effective prescription of spleen and stomach disease in the treatment of spleen and stomach disease in the treatment of spleen and stomach disease was carried out by using the V2.5 software of TCM inheritance platform to analyze the distribution of sexual taste，frequency statistics，prescription law，core combination and new prescription.Results A total of 137 effective prescriptions were collected，involving 159 flavors of traditional Chinese medicine.25 drugs with frequency ≥10 were used，and the most common drugs were wen，xin and spleen.The number of support was set to 18 and the confidence was 0.6.15 common drug pairs and combinations were obtained; based on the software complex entropy hierarchical clustering method，32 core groups for clustering of new parties were obtained，and 16 new parties were aggregated.Conclusion The treatment of spleen and stomach disease in the treatment of spleen and stomach disease is mainly based on warming spleen and yang.In terms of medication，Xinwen medicine is mainly used for yang qi，supplemented by sweet medicine to nourish and neutralize medicinal properties.
Keywords：Li Yongcui;《Zheng Zhi Hui Bu》;Chinese Medicine Inheritance Auxiliary Platform;Spleen and Stomach Diseases;Medication Rule
《證治汇补》乃清代医学家李用粹的代表著作。李用粹，字修之，号惺庵，明末清初人，其幼承家学，博览医书，晚年博采轩歧以来诸书，条贯辨析，标其举要，集为《证治汇补》[1]。《证治汇补》共8卷，分为提纲、内因、外体、上窍、胸膈、腹胁、腰膝及下窍8门，其中包括内科、杂病82类病症，每症中含有病因、外候、条目、辨证、脉象、治法、劫法、用药、附证及方剂。每项内均“集古人书而汇集之，删其繁而存其要，补其缺而正其偏”，故名之为《证治汇补》[1]。可以说《证治汇补》是一部中医临床工作者的必备参考书。笔者运用数据挖掘的方式，通过中医传承辅助平台V 2.5软件分析《证治汇补》中治疗脾胃病的用药规律，以期为中医治疗脾胃病提供依据。, 百拇医药(王嘉芮 喻斌)
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