李辰浩 张玉蓉 赵微

    【摘 要】 文章基于“肝胆相表里”理论 从中医对非酒精性脂肪肝病归属、辨证分型及病机的认识 “肝胆相表里”的理论基础与临床研究等方面探讨该理论在非酒精性脂肪肝病中的运用概况 表明以疏肝为主加以利胆的治疗原则在非酒精性脂肪肝病的辨证治疗中具有显著疗效 为非酒精性脂肪肝病的临床和科研研究提供了新思路。

    【关键词】 非酒精性脂肪肝病;肝胆相表里;研究概况

    Abstract：Based on the theory of “the liver sharing an interior-exterior relationship with gallbladder”， the application of this theory in non-alcoholic fatty liver disease was discussed through literature research. According to relevant clinical literature，the principle of liver-soothing combined with gallbladder tonifying has a good effect on the differentiation of symptoms and signs in the treatment of NAFLD， which proves the practical significance of the application of the theory of “inside and outside the liver and gallbladder” in the treatment of NAFLD.

    Keywords：Nonalcoholic Fatty Liver Disease; The Liver Sharing an Interior-exterior Relationship With gallbladder;Research Summary

    非酒精性脂肪肝病(Non-alcoholic fatty liver disease NAFLD)主要是由于不合理的饮食和生活习惯引起的各种非酒精性因素导致机体代谢紊乱 脂类物质在肝脏中堆积过度引起的一系列肝脏应激性病变 其发病与基因遗传和胰岛素抵抗(Insulin Resistance IR)密切相关[1-2]。随着社会和经济的发展 人们的生活方式和餐饮习惯也发生了改变 NAFLD在普通成人中的患病率已经介于6.3%～45% 成为了全球最常见的慢性肝病 包括中国在内的亚洲多数国家NAFLD患病率处于中上水平(>25% )[3-4] ......