基于脑-肠轴理论探析“胃不和则卧不安”
刘小庆 张怡【摘要】文章阐述了“胃不和”与“卧不安”及二者间的关系,并用现代医学脑-肠轴理论探讨“胃不和”“卧不安”的内在机制,以期为临床失眠和胃肠疾病的治疗提供新思路。
【关键词】胃不和;卧不安;脑-肠轴;脑肠肽
【中图分类号】R256【文献标志码】 A【文章编号】1007-8517(2022)04-0016-04
Discuss “Disharmony of Stomach Leads to Insomnia” Based on the Theory of Brain-gut Axis
LIU XiaoqingZHANG Yi
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China
Abstract:This paper expounds the relationship between “disharmony of stomach” and “insomnia”, and also discusses the internal mechanism between them by using the theory of brain-gut axis of modern medicine,in order to provide new ideas for clinical treatment of insomnia and gastrointestinal diseases.
Keywords:Disharmony of Stomach;Insomnia;Brain-Gut Axis;Brain-Gut Peptide
“胃不和则卧不安”是中医颇具特色的经典观点。《灵枢·动输》言:“胃气上注于肺,其悍气上冲头者……入络脑”[1],表明胃与脑相通。现代医学提出的脑-肠轴理论,将脑与肠之间的关系做了更加具体的解释[2]。本文旨在从脑-肠轴角度探讨“胃不和则卧不安”,让现代医学解释说明中医理论,以期为临床治疗失眠和胃肠疾病提供新思路。
1“胃不和”与“卧不安”
1.1胃不和“胃不和”,名曰“胃”,实则包括阳明经、脾胃、大小肠[3]。《灵枢·本输》云:“大肠小肠,皆属于胃,是足阳明也。”从位置上来说,大肠小肠与胃紧密相连,在生理功能上,二者与胃共同受纳腐熟饮食物,因此古代常将胃肠统称作胃。《伤寒论》[4]阳明病纲提所说的:“阳明之为病 ......
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