金散外敷干预MEK(实验研究)

金散外敷干预MEK/ERK信号通路治疗肉芽肿性小叶性乳腺炎模型大鼠的作用机制

http://www.100md.com 2025年7月22日中国民族民间医药·下半月 2025年第5期

     【天键词】肉牙肿性小叶性孔腺炎；金更散；MEK/EKK信号通路

    【中图分类号】R285.5 【文献标志码】A 【文章编号】1007-8517(2025)10-0047-06

    DOI：10.3969/j. issn.1007-8517.2025.10.zgmzmjyyzz202510009

    Mechanism of Jinhuang Powder External Application Intervention on MEK/ERK Signaling Pathwayin theTreatmentof GranulomatousLobularMastitisModel Rats

    LI Qianyan1ZHANG Ying2LI Benfa3HUANG Donghan3WANG Mengyuan4LI Zhuoling1MA Siqi1HUANG Min1* 1.Yunnan Universityof Traditional Chinese Medicine，Kunming65o5O0，China；2.WuhanFirstHospital，Wuhan430022， China；3.The First Afiliated Hospitalof Yunnan Universityof Traditional Chinese Medicine，Kunming 65O021，China; 4.YunnanVocational College of Transportation，Kunming 65O3Oo，China

    Abstract：ObjectiveToexploretheefectofJinhuang Powderonregulating the MEK/ERK signaling pathwayinrats with granulomatouslobularmastitis(GLM).MethodThirtyfemaleSDratswererandomlydividedintothre groups：blankcontrol group，model group，andJinhuangPowdergroup.Takeoilinmilksuspensionandinjectitintothefourthpairofmammaryglandsofrats toestablishaGLMmodel；TheblankcontrolgroupratswereinjectedwithanequalamountofphysiologicalsalineatthesamesiteAfter thesuccessulestablishmentofthemodel ......

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