广西壮族自治区花红药业股份有限公司，广西 柳州 545007

    HPLC法测定金松止痒洗液中梣酮的含量

    陆晖刘春明黄秀花

    广西壮族自治区花红药业股份有限公司，广西 柳州 545007

    目的建立金松止痒洗液中梣酮的含量测定方法。方法采用HPLC法，以Zorbax XDB-C18为分析柱(4.6mm×150mm,5μm)，甲醇-水(60∶40)为流动相，流速1ml·min-1，检测波长为236nm。结果梣酮在0.02～0.25μg线性关系良好(R=0.9999),平均加样回收率为98.51%，RSD为0.91%(n=6)。结论本法准确、简便、重复性好，可作为金松止痒洗液的质量控制方法。

    金松止痒洗液；梣酮；HPLC

    Abstract:ObjectiveTo establish an HPLC method for determining the content of fraxinellone in Jinsongzhiyang lotion.Methodsmethanol-water(60∶40)，the flow rate was 1.0 ml·min-1，and the deterring wavelength was 236nm.ResultsThe linear range of gaillic acid was from 0.02μg to 0.25μg(R=0.9999).The average recovery rate was 98.51%,RSD was 0.91%(n=6).ConlusionThe method was accurate and simple with high repeatablility,which can be used for the qualtity control of Jinsongzhiyang lotion.

    Keywords:Jinsongzhiyang lotion；fraxinellone；HPLC

    金松止痒洗液为我公司独家品种(国药准字B20020210) ......