【摘 要】 目的：采用单因素考察和正交试验法对银灵康胶囊提取工艺进行优化。方法：以绿原酸和落新妇苷含量为指标，采用L9(34)正交表安排正交试验，对提取溶剂乙醇的浓度、提取溶剂量、提取时间、提取次数四个因素进行了优化。结果：通过直观分析，方差分析和综合评价方法，确定最佳提取工艺为：采用回流提取，乙醇浓度85%，料液比1∶10，提取时间2 h，提取次数2次。结论：优选出的提取工艺稳定、可行、重复性好，可作为银灵康胶囊的提取工艺。

    【关键词】 银灵康胶囊;正交试验;提取工艺

    【中图分类号】R284 【文献标志码】 A 【文章编号】1007-8517(2019)17-0020-08

    Abstract：Objective To optimize the ethanol extraction process of Yinlingkang capsules was studied by the single factor test and orthogonal design with extractive yield and the contents of chlorogenic acid and astilbin as markers. Methods Four facors were studied in this experiment ......