内质网应激蛋白ATF4调控STAT3信号通路促进黑色素瘤细胞生长及转移的研究(4)
[12]Ameri K,Lewis CE,Raida M,et al.Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells[J].Blood,2004,103(5):1876-1882.
[13]Dey S,Sayers CM,Verginadis II,et al. ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis[J].J Clin Invest,2015,125(7):2592-2608.
[14]Suzuki T,Osumi N,Wakamatsu Y.Stabilization of ATF4 protein is required for the regulation of epithelial-mesenchymal transition of the avian neural crest[J].Dev Biol,2010,344(2):658-668.
[15]Nagelkerke A,Bussink J,Mujcic H,et al.Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response[J].Breast Cancer Res,2013,15(1):R2.
[16]Croft A,Tay KH,Boyd SC,et al.Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress[J].J Invest Dermatol,2014,134(2):488-497.
[17]Ma XH,Piao SF,Dey S,et al.Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma[J].J Clin Invest,2014,124(3):1406-1417.
[18]Shan B,Wang X,Wu Y,et al.The metabolic ER stress sensor IRE1alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity[J]. Nat Immunol,2017,18(5):519-529.
[19]Shao M,Shan B,Liu Y,et al.Hepatic IRE1alpha regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARalpha axis signalling[J].Nat Commun,2014,5:3528.
[20]Ding BB,Yu JJ,Yu RY,et al.Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas[J].Blood,2008,111(3):1515-1523.
[21]Darnell JE.Validating Stat3 in cancer therapy[J].Nat Med,2005,11(6):595-596.
[22]Kortylewski M,Jove R,Yu H.Targeting STAT3 affects melanoma on multiple fronts[J].Cancer Metastasis Rev,2005,24(2):315-327.
[23]Kortylewski M,Kujawski M,Wang T,et al.Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity[J].Nat Med,2005,11(12):1314-1321.
[收稿日期]2018-04-28 [修回日期]2018-05-28
編辑/朱婉蓉, http://www.100md.com(张学军 亓发芝)
[13]Dey S,Sayers CM,Verginadis II,et al. ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis[J].J Clin Invest,2015,125(7):2592-2608.
[14]Suzuki T,Osumi N,Wakamatsu Y.Stabilization of ATF4 protein is required for the regulation of epithelial-mesenchymal transition of the avian neural crest[J].Dev Biol,2010,344(2):658-668.
[15]Nagelkerke A,Bussink J,Mujcic H,et al.Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response[J].Breast Cancer Res,2013,15(1):R2.
[16]Croft A,Tay KH,Boyd SC,et al.Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress[J].J Invest Dermatol,2014,134(2):488-497.
[17]Ma XH,Piao SF,Dey S,et al.Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma[J].J Clin Invest,2014,124(3):1406-1417.
[18]Shan B,Wang X,Wu Y,et al.The metabolic ER stress sensor IRE1alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity[J]. Nat Immunol,2017,18(5):519-529.
[19]Shao M,Shan B,Liu Y,et al.Hepatic IRE1alpha regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARalpha axis signalling[J].Nat Commun,2014,5:3528.
[20]Ding BB,Yu JJ,Yu RY,et al.Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas[J].Blood,2008,111(3):1515-1523.
[21]Darnell JE.Validating Stat3 in cancer therapy[J].Nat Med,2005,11(6):595-596.
[22]Kortylewski M,Jove R,Yu H.Targeting STAT3 affects melanoma on multiple fronts[J].Cancer Metastasis Rev,2005,24(2):315-327.
[23]Kortylewski M,Kujawski M,Wang T,et al.Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity[J].Nat Med,2005,11(12):1314-1321.
[收稿日期]2018-04-28 [修回日期]2018-05-28
編辑/朱婉蓉, http://www.100md.com(张学军 亓发芝)