微针疗法联合PRP治疗痤疮凹陷性瘢痕疗效分析(1)
[摘要]目的：探讨微针联合富血小板血浆 ( Platelet-rich Plasma，PRP) 在治疗痤疮凹陷性瘢痕中的临床应用及疗效评价。方法：选取2014年5月-2017年10月笔者科室就诊的57例痤疮凹陷性瘢痕患者，其中27例接受微针联合RPR治疗，15例接受单纯微针治疗，另外15例接受单纯RPR治疗。微针联合RPR治疗组，先行微针治疗瘢痕区，后涂抹PRP于治疗区；单纯微针治疗组予以瘢痕处单纯微针治疗；单纯RPR组予以瘢痕处直接涂抹RPR。三组治疗均1个月1次，6次为1个疗程，分别在治疗3次后、6次后和疗程结束后3个月对患者的瘢痕治疗效果进行评估。结果：与单纯微针治疗和单纯RPR治疗组相比，27例接受微针联合RPR治疗患者面部痤疮凹陷性瘢痕得到明显改善，随着治疗次数的增多，总有效率越高。结论：微针疗法联合PRP治疗痤疮凹陷性瘢痕，辅以规范的术后护理，效果确切，值得临床推广应用。
[关键词]微针疗法；富血小板血浆；痤疮；凹陷性瘢痕；疗效评价
[中图分类号]R619+.6 [文献标志码]A [文章编号]1008-6455(2018)10-0027-03
, http://www.100md.com
Abstract： Objective To explore the clinical application and therapeutic evaluation of microacupuncture combined with Platelet-rich Plasma (PRP) in the treatment of acne depression scar. Methods A total of 57 patients were selected from May 2014 to October 2017. 27 patients received microacupuncture and RPR treatment， 15 patients received microacupuncture treatment， and 15 patients received RPR treatment. The microacupuncture and RPR treatment group were firstly treated with microacupuncture and then PRP were used to the treatment area. In the microacupuncture treatment group， the scar was treated with microacupuncture only. The RPR treatment was applied to the scars in the RPR group.All the above treatments were performed once a month with 6 times as a course， and the effect of treatment was evaluated after 3 times of treatment， 6 times after treatment and 3 months after the end of treatment. Results 27 patients were treated with microacupuncture and RPR had a appearance improvement of the acne scar. Besides， the more times of treatment were received，the higher total effective rate wound be compared with microacupuncture treatment and RPR treatment respectively. Conclusion Microacupuncture combined with PRP is effective in the treatment of acne scar with normative nursing care after operation，and it is worthy of clinical promotion and application.
, 百拇医药
Key words： microacupuncture； Platelet-rich Plasma； acne； depression scar； therapeutic evaluation
痤疮是一种毛囊皮脂腺的慢性炎症性疾病，为多因素疾病，临床表现多样，具有一定的损容性。其中结节或囊肿性的损害，可化脓破溃后形成窦道，最终形成凹陷性瘢痕。与正常皮肤相比，凹陷性瘢痕表现为皮肤表层组织部分缺失，根据形态可分为冰锥样、车厢样及浅碟样瘢痕，局部可伴随色素改变[1]。目前临床上治疗痤疮凹陷性瘢痕的方法主要为超脉冲CO2点阵激光，但治療后易出现红斑、疼痛、色素沉着及皮肤干燥等不良反应[2]，恢复时间相对较长，部分患者较难接受。大量研究证明，PRP可以促进软骨组织和骨组织的再生，同时兼有抗炎、抗菌的作用。近年来，临床上已经广泛应用于骨与软组织重建手术、整形手术、糖尿病足难治性溃疡和慢性皮肤溃疡等[3-6]。美容医学领域也逐渐应用PRP技术来促进局部组织或细胞的再生，以达到美容目的[7-8]。2014年5月-2017年10月，笔者科室采用微针疗法联合PRP治疗痤疮凹陷性瘢痕患者，取得了较满意的疗效，现报道如下。
1 资料和方法
1.1 临床资料：选择笔者科室2014年5月-2017年10月就诊的符合入选标准的57例痤疮凹陷性瘢痕患者为研究对象，其中男34例，女23例；年龄17～35岁，平均(24.7±5.21)岁；病程1～17年，平均病程(5.04±2.17)年。, 百拇医药(崔晓美 丁晓东 陈晓明 姚晓东 许攀 朱文艳)
[关键词]微针疗法；富血小板血浆；痤疮；凹陷性瘢痕；疗效评价
[中图分类号]R619+.6 [文献标志码]A [文章编号]1008-6455(2018)10-0027-03
, http://www.100md.com
Abstract： Objective To explore the clinical application and therapeutic evaluation of microacupuncture combined with Platelet-rich Plasma (PRP) in the treatment of acne depression scar. Methods A total of 57 patients were selected from May 2014 to October 2017. 27 patients received microacupuncture and RPR treatment， 15 patients received microacupuncture treatment， and 15 patients received RPR treatment. The microacupuncture and RPR treatment group were firstly treated with microacupuncture and then PRP were used to the treatment area. In the microacupuncture treatment group， the scar was treated with microacupuncture only. The RPR treatment was applied to the scars in the RPR group.All the above treatments were performed once a month with 6 times as a course， and the effect of treatment was evaluated after 3 times of treatment， 6 times after treatment and 3 months after the end of treatment. Results 27 patients were treated with microacupuncture and RPR had a appearance improvement of the acne scar. Besides， the more times of treatment were received，the higher total effective rate wound be compared with microacupuncture treatment and RPR treatment respectively. Conclusion Microacupuncture combined with PRP is effective in the treatment of acne scar with normative nursing care after operation，and it is worthy of clinical promotion and application.
, 百拇医药
Key words： microacupuncture； Platelet-rich Plasma； acne； depression scar； therapeutic evaluation
痤疮是一种毛囊皮脂腺的慢性炎症性疾病，为多因素疾病，临床表现多样，具有一定的损容性。其中结节或囊肿性的损害，可化脓破溃后形成窦道，最终形成凹陷性瘢痕。与正常皮肤相比，凹陷性瘢痕表现为皮肤表层组织部分缺失，根据形态可分为冰锥样、车厢样及浅碟样瘢痕，局部可伴随色素改变[1]。目前临床上治疗痤疮凹陷性瘢痕的方法主要为超脉冲CO2点阵激光，但治療后易出现红斑、疼痛、色素沉着及皮肤干燥等不良反应[2]，恢复时间相对较长，部分患者较难接受。大量研究证明，PRP可以促进软骨组织和骨组织的再生，同时兼有抗炎、抗菌的作用。近年来，临床上已经广泛应用于骨与软组织重建手术、整形手术、糖尿病足难治性溃疡和慢性皮肤溃疡等[3-6]。美容医学领域也逐渐应用PRP技术来促进局部组织或细胞的再生，以达到美容目的[7-8]。2014年5月-2017年10月，笔者科室采用微针疗法联合PRP治疗痤疮凹陷性瘢痕患者，取得了较满意的疗效，现报道如下。
1 资料和方法
1.1 临床资料：选择笔者科室2014年5月-2017年10月就诊的符合入选标准的57例痤疮凹陷性瘢痕患者为研究对象，其中男34例，女23例；年龄17～35岁，平均(24.7±5.21)岁；病程1～17年，平均病程(5.04±2.17)年。, 百拇医药(崔晓美 丁晓东 陈晓明 姚晓东 许攀 朱文艳)
参见：首页 > 医疗版 > 疾病专题 > 皮肤科 > 皮肤附属器官疾病 > 痤疮(青春痘)