提高脂肪移植存活成功率的研究进展(3)
4 小结
综上所述,临床上对脂肪组织的处理从最初的大体积移植到目前最新的SVF-gel移植技术,以及各种辅助因素的研究,为脂肪移植提供了更广阔的前景与思路。SVF-gel移植技术的高保留率及ECM对细胞的支架作用,为脂肪移植技术开拓了新的思路,需进一步的研究与发展,相信随着移植技术的不断完善,移植存活率将逐步提升,使脂肪移植更广泛的应用于临床。
[参考文献]
[1]Kolle SF,Fischer-Nielsen A,Mathiasen AB,et al. Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial[J].Lancet,2013,382(9898):1113-1120.
, http://www.100md.com
[2]Khouri RK,Rigotti G,Cardoso E,et al.Megavolume autologous fat transfer: part II.Practice and techniques[J].Plast Reconstr Surg,2014,133(6):1369-1377.
[3]Padoin AV,Braga-Silva J,Martins P,et al.Sources of processed lipoaspirate cells: influence of donor site on cell concentration[J].Plast Reconstr Surg,2008,122(2):614-618.
[4]Bertheuil N,Varin A,Carloni R,et al Mechanically isolated stromal vascular fraction by nanofat emulsification techniques[J].Plast Reconstr Surg,2017,140(3):508e-509e.
, 百拇医药
[5]Abbo O,Taurand M,Monsarrat P,et al.Comparison between pediatric and adult adipose mesenchymal stromal cells[J].Cytotherapy,2017,19(3):395-407.
[6]Kato H,Mineda K,Eto H,et al.Degeneration,regeneration,and cicatrization after fat grafting: dynamic total tissue remodeling during the first 3 months[J].Plast Reconstr Surg, 2014,133(3):303e-313e.
[7]Veber M,Tourasse C,Toussoun G,et al.Radiographic findings after breast augmentation by autologous fat transfer[J].Plast Reconstr Surg,2011,127(3):1289-1299.
, 百拇医药
[8]Illouz YG.The fat cell "graft":a new technique to fill depressions[J].Plast Reconstr Surg, 1986,78(1):122-123.
[9]Coleman SR.Facial recontouring with lipostructure[J].Clin Plast Surg,1997,24(2):347-367.
[10]Pu LL,Coleman SR,Cui X,et al.Autologous fat grafts harvested and refined by the Coleman technique:a comparative study[J].Plast Reconstr Surg,2008,122(3):932-937.
[11]Zuk PA,Zhu M,Mizuno H,et al.Multilineage cells from human adipose tissue: implications for cell-based therapies[J].Tissue Eng,2001,7(2):211-228.
, 百拇医药
[12]Yoshimura K,Suga H,Eto H.Adipose-derived stem/progenitor cells: roles in adipose tissue remodeling and potential use for soft tissue augmentation[J].Regen Med,2009,4(2):265-273.
[13]孫凯,甄永环,刘永葆.血管基质成分提升面部脂肪移植存活率的临床观察[J].中国美容医学, 2014,23(4):267-269.
[14]Katare R,Riu F,Mitchell K,et al.Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132[J].Circ Res,2011,109(8):894-906., http://www.100md.com(柳丛 李云霞 叶媛 邹敬江 胡葵葵)
综上所述,临床上对脂肪组织的处理从最初的大体积移植到目前最新的SVF-gel移植技术,以及各种辅助因素的研究,为脂肪移植提供了更广阔的前景与思路。SVF-gel移植技术的高保留率及ECM对细胞的支架作用,为脂肪移植技术开拓了新的思路,需进一步的研究与发展,相信随着移植技术的不断完善,移植存活率将逐步提升,使脂肪移植更广泛的应用于临床。
[参考文献]
[1]Kolle SF,Fischer-Nielsen A,Mathiasen AB,et al. Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial[J].Lancet,2013,382(9898):1113-1120.
, http://www.100md.com
[2]Khouri RK,Rigotti G,Cardoso E,et al.Megavolume autologous fat transfer: part II.Practice and techniques[J].Plast Reconstr Surg,2014,133(6):1369-1377.
[3]Padoin AV,Braga-Silva J,Martins P,et al.Sources of processed lipoaspirate cells: influence of donor site on cell concentration[J].Plast Reconstr Surg,2008,122(2):614-618.
[4]Bertheuil N,Varin A,Carloni R,et al Mechanically isolated stromal vascular fraction by nanofat emulsification techniques[J].Plast Reconstr Surg,2017,140(3):508e-509e.
, 百拇医药
[5]Abbo O,Taurand M,Monsarrat P,et al.Comparison between pediatric and adult adipose mesenchymal stromal cells[J].Cytotherapy,2017,19(3):395-407.
[6]Kato H,Mineda K,Eto H,et al.Degeneration,regeneration,and cicatrization after fat grafting: dynamic total tissue remodeling during the first 3 months[J].Plast Reconstr Surg, 2014,133(3):303e-313e.
[7]Veber M,Tourasse C,Toussoun G,et al.Radiographic findings after breast augmentation by autologous fat transfer[J].Plast Reconstr Surg,2011,127(3):1289-1299.
, 百拇医药
[8]Illouz YG.The fat cell "graft":a new technique to fill depressions[J].Plast Reconstr Surg, 1986,78(1):122-123.
[9]Coleman SR.Facial recontouring with lipostructure[J].Clin Plast Surg,1997,24(2):347-367.
[10]Pu LL,Coleman SR,Cui X,et al.Autologous fat grafts harvested and refined by the Coleman technique:a comparative study[J].Plast Reconstr Surg,2008,122(3):932-937.
[11]Zuk PA,Zhu M,Mizuno H,et al.Multilineage cells from human adipose tissue: implications for cell-based therapies[J].Tissue Eng,2001,7(2):211-228.
, 百拇医药
[12]Yoshimura K,Suga H,Eto H.Adipose-derived stem/progenitor cells: roles in adipose tissue remodeling and potential use for soft tissue augmentation[J].Regen Med,2009,4(2):265-273.
[13]孫凯,甄永环,刘永葆.血管基质成分提升面部脂肪移植存活率的临床观察[J].中国美容医学, 2014,23(4):267-269.
[14]Katare R,Riu F,Mitchell K,et al.Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132[J].Circ Res,2011,109(8):894-906., http://www.100md.com(柳丛 李云霞 叶媛 邹敬江 胡葵葵)