活血美颗粒联合中药退红面膜治疗面部毛细血管扩张症疗效观察(1)
[摘要]目的：探讨活血美颗粒联合自制中药退红面膜治疗面部毛细血管扩张症的临床疗效。方法：收集面部单纯性毛细血管扩张症患者80例，随机分为两组。对照组：40例，外用他克莫司软膏，25mg/次，2次/d；治疗组：40例，服用活血美颗粒联合自制中药退红面膜。连续治疗7d为1个疗程。两组连续治疗4个疗程后观察临床症状及不良反应，利用VISIA 软件判定疗效。结果：治疗4个疗程后，治疗组总有效率为92.5%，对照组为67.5%，治疗组疗效优于对照组，有显著性差异(P<0.05)；治疗组患者临床症状得到明显改善，副作用小，而且停药后复发率较低。结论：活血美颗粒联合中药退红面膜治疗面部毛细血管扩张症疗效显著，可临床推广应用。
[关键词]活血美颗粒；他克莫司；皮肤光老化；毛细血管扩张症；中药退红面膜
[中图分类号]R322.99 [文献标志码]A [文章编号]1008-6455(2018)12-0136-03
, http://www.100md.com
The Effect Observation of Huoxuemei Granule Combined with Chinese Medicine Redness-removing Facial Mask in the Treatment of Facial Telangiectasia
FENG Ju-qing，WANG Jian-jun，TIE Xiao-ying，HAI Ni，WANG Jiang-hua
(XI’an Haitang Vocational College，Xi’an 710038，Shaanxi，China)
Abstract： Objective To investigate the clinical effect of Huoxuemei granule combined with Chinese Medicine redness-removing facial mask to treat facial telangiectasia. Methods 80 patients with facial simple telangiectasia were randomly divided into two groups. Control group： 40 cases， external use of tacrolimus ointment， 25 mg/times， 2 times/d； Treatment group： 40 cases， take Huoxuemei granule combined with redness-removing facial mask. Continuous treatment for 7 days as one course. The two groups were observed clinical symptoms and adverse reactions after 4 consecutive treatment courses and used VISIA software to determine the efficacy. Results After 4 treatment courses， the total effective rate was 92.5% in the treatment group and 67.5% in the control group. The clinical symptoms of the patients in the treatment group were obviously improved(P<0.05)；the side effects were small， and the recurrence rate was low after stopping the drug. Conclusion Huoxuemei granule combined with Chinese Medicine redness-removing facial mask is effective in the treatment of facial telangiectasia， and can be applied clinically.
, 百拇医药
Key words： huoxuemei granules； tacrolimus； skin photoage； telangiectasia； chinese medicine redness-removing facial mask
面部毛細血管扩张症是一种临床常见的面部碍容性疾病，临床表现为肉眼可见扩张的毛细血管，常伴有红色或紫红色斑状、点状、线状或星状等，常见原因主要为紫外线辐射导致的皮肤光老化引起[1-3]，因影响容貌美，患者求治心切。2016年5月-2016年12月，笔者单位采用活血美颗粒联合自制中药退红面膜治疗面部毛细血管扩张症患者，取得了较好疗效，现报道如下。
1 资料和方法
1.1 一般资料：本研究所选面部毛细血管扩张症患者均来自西安海棠职业学院附属海棠中医美容院就诊病例，共80例，均具有长期日光照射史且有面部毛细血管扩张症状。采用随机数字表法将其分为治疗组与对照组。治疗组：40例，其中男5例，女35例，年龄15～20岁；对照组：40例，其中男6例，女34例，年龄16～21岁。两组患者性别、年龄及病程比较，差异无统计学意义(P>0.05)，具有可比性。见表1。
1.2 诊断标准：结合临床经验制定皮肤光老化所致毛细血管扩张症标准如下[5]：皮肤可见粗细不等的毛细血管扩张；颜色淡红、鲜红或紫红色；压之不退色；对称或不对称，局限或泛发；无明显炎症性表现。
1.3 排除标准：①敏感性皮肤患者；②患有糖尿病、内分泌失调、癫痫病、血友病等或瘢痕体质者；③妊娠及哺乳期女性；④近期正在全身或局部使用类固醇药物、抗凝血剂或光敏性药物者；⑤活跃的单纯性疱疹；⑥怀疑有皮肤癌或者皮肤癌前病变者。, http://www.100md.com(冯居秦 王建军 帖晓瑛 海妮 王江华)
[关键词]活血美颗粒；他克莫司；皮肤光老化；毛细血管扩张症；中药退红面膜
[中图分类号]R322.99 [文献标志码]A [文章编号]1008-6455(2018)12-0136-03
, http://www.100md.com
The Effect Observation of Huoxuemei Granule Combined with Chinese Medicine Redness-removing Facial Mask in the Treatment of Facial Telangiectasia
FENG Ju-qing，WANG Jian-jun，TIE Xiao-ying，HAI Ni，WANG Jiang-hua
(XI’an Haitang Vocational College，Xi’an 710038，Shaanxi，China)
Abstract： Objective To investigate the clinical effect of Huoxuemei granule combined with Chinese Medicine redness-removing facial mask to treat facial telangiectasia. Methods 80 patients with facial simple telangiectasia were randomly divided into two groups. Control group： 40 cases， external use of tacrolimus ointment， 25 mg/times， 2 times/d； Treatment group： 40 cases， take Huoxuemei granule combined with redness-removing facial mask. Continuous treatment for 7 days as one course. The two groups were observed clinical symptoms and adverse reactions after 4 consecutive treatment courses and used VISIA software to determine the efficacy. Results After 4 treatment courses， the total effective rate was 92.5% in the treatment group and 67.5% in the control group. The clinical symptoms of the patients in the treatment group were obviously improved(P<0.05)；the side effects were small， and the recurrence rate was low after stopping the drug. Conclusion Huoxuemei granule combined with Chinese Medicine redness-removing facial mask is effective in the treatment of facial telangiectasia， and can be applied clinically.
, 百拇医药
Key words： huoxuemei granules； tacrolimus； skin photoage； telangiectasia； chinese medicine redness-removing facial mask
面部毛細血管扩张症是一种临床常见的面部碍容性疾病，临床表现为肉眼可见扩张的毛细血管，常伴有红色或紫红色斑状、点状、线状或星状等，常见原因主要为紫外线辐射导致的皮肤光老化引起[1-3]，因影响容貌美，患者求治心切。2016年5月-2016年12月，笔者单位采用活血美颗粒联合自制中药退红面膜治疗面部毛细血管扩张症患者，取得了较好疗效，现报道如下。
1 资料和方法
1.1 一般资料：本研究所选面部毛细血管扩张症患者均来自西安海棠职业学院附属海棠中医美容院就诊病例，共80例，均具有长期日光照射史且有面部毛细血管扩张症状。采用随机数字表法将其分为治疗组与对照组。治疗组：40例，其中男5例，女35例，年龄15～20岁；对照组：40例，其中男6例，女34例，年龄16～21岁。两组患者性别、年龄及病程比较，差异无统计学意义(P>0.05)，具有可比性。见表1。
1.2 诊断标准：结合临床经验制定皮肤光老化所致毛细血管扩张症标准如下[5]：皮肤可见粗细不等的毛细血管扩张；颜色淡红、鲜红或紫红色；压之不退色；对称或不对称，局限或泛发；无明显炎症性表现。
1.3 排除标准：①敏感性皮肤患者；②患有糖尿病、内分泌失调、癫痫病、血友病等或瘢痕体质者；③妊娠及哺乳期女性；④近期正在全身或局部使用类固醇药物、抗凝血剂或光敏性药物者；⑤活跃的单纯性疱疹；⑥怀疑有皮肤癌或者皮肤癌前病变者。, http://www.100md.com(冯居秦 王建军 帖晓瑛 海妮 王江华)