吴丽 江婷婷 李静 张劲东

    [摘要]目的：探討射频微针联合表皮生长因子治疗中重度痤疮的有效性，观察治疗过程中产生的不良反应，评估其安全性及对痤疮瘢痕权重评分(ECCA)的影响。方法：选取2018年5月-2020年6月笔者科室收治的76例中重度痤疮患者为研究对象，按随机数字法分为对照组和观察组，每组38例。对照组：单用射频微针进行治疗，1个月治疗1次;观察组：在对照组基础上加用表皮生长因子外用溶液外涂。两组治疗均持续3个月，比较两组治疗效果，观察治疗过程中的不良反应，评估治疗的安全性及对ECCA评分的影响。结果：治疗后，观察组总有效率94.59%，与对照组(88.89%)比较无统计学意义(P>0.05);治疗期间，观察组不良反应发生率32.43%，低于对照组的58.33%，两组比较有统计学意义(P0.05);治疗后，两组ECCA评分均低于治疗前，观察组低于对照组(P0.05). The incidence of adverse reactions in the observation group during treatment was 32.43%， which was lower than 58.33% in the control group? (P0.05). After treatment， they were lower than those before treatment， and the observation group were lower than the control group (P0.05) ......