刘晓雪

    [關键词]特应性皮炎;他克莫司;间断应用;皮肤胶原

    [中图分类号]R758.22? ? [文献标志码]A? ? [文章编号]1008-6455(2021)12-0063-04

    Effect of Intermittent Application of Topical Tacrolimus on Skin Collagen Synthesis in Patients with Atopic Dermatitis

    LIU Xiao-xue

    (Department of Dermatology，People's Hospital of Xiangzhou District，Hubei Province，

    Xiangyang 441000，Hubei，China)

    Abstract：? Objective? To explore the effect of intermittent application of topical tacrolimus on skin collagen synthesis in patients with atopic dermatitis (AD).? Methods? A total of 104 AD patients admitted to our hospital from march 2018 to march 2020 were randomly divided into a control group (51 cases) and an observation group (53 cases). Both groups of patients were treated with tacrolimus ointment for the first stage of treatment. In the control group ......