宋世珅 钱青 高春岩 申宇鸿

    [摘要]目的：探討毫针联合外用重组人碱性成纤维细胞生长因子在面部年轻化中的应用效果。方法：按照随机数字表法将2020年1月-2020年12月在笔者医院进行面部年轻化治疗的110例就医者分为对照组与观察组，每组55例。对照组就医者给予面部毫针治疗，观察组就医者给予面部毫针联合外用重组人碱性成纤维细胞生长因子治疗。比较两组就医者的治疗效果、面部衰老评分、就医者满意度评分及不良反应。结果：观察组的总有效率明显高于对照组(96.36% vs 81.82%，P<0.05)。治疗后，观察组的面部衰老评分明显低于对照组[(0.37±0.15)分vs(1.02±0.59)分，P<0.05]，就医者满意度评分明显高于对照组[(84.77±6.59)分vs(70.11±5.40)分，P<0.05]。两组均没有发生明显不良反应。结论：面部毫针联合外用重组人碱性成纤维细胞生长因子在面部年轻化中的应用效果显著，安全性好，就医者满意度高。

    [关键词]面部年轻化;面部毫针;重组人碱性成纤维细胞生长因子;面部衰老;满意度

    [中图分类号]R245.31+1? ? [文献标志码]B? ? [文章编号]1008-6455(2022)06-0115-03

    Millineedle Combined with Topical Recombinant Human Alkaline Fibroblast Growth Factor in Facial Rejuvenation

    SONG Shishen，QIAN Qing，GAO Chunyan，SHEN Yuhong

    (Department of Dermatology，Beijing Hepingli Hospital，Beijing 100013，China)

    Abstract： Objective Compared the application effect of facial millineedles and facial millineedles combined with topical recombinant human alkaline fibroblast growth factor in facial rejuvenation. Methods According to the random number table method， 110 patients who received facial rejuvenation treatment in author hospital from January 2020 to December 2020 were divided into control group and observation group ......