王林 陈剑利 高小春 邹才学

    [摘要]目的：探讨两种不同敷料联合自体微粒皮种植术对深Ⅱ度烧伤的疗效。方法：选取2018年9月-2020年10月在笔者医院就诊的90例深Ⅱ度烧伤患者，按随机数表法分为对照组和试验组，各45例。对照组给予湿润烧伤膏联合自体微粒皮种植术进行治疗；试验组给予水凝膠敷料联合自体微粒皮种植术进行治疗。比较两组患者疗效、创面愈合情况、温哥华瘢痕量表(Vancouver scar scale，VSS)评分、血清致痛因子水平及不良反应。结果：治疗3周后，两组患者总有效率比较差异无统计学意义(P>0.05)；试验组患者创面上皮形成时间、创面愈合时间及不良反应发生率数值均低于对照组(P<0.05)；治疗3周后，两组血清前列腺素E2(Prostaglandin，PGE2)、神经肽(Neuropetide Y，NPY)、5-羟色胺(5-Hydroxytryptamine，5-HT)水平均降低，且试验组低于对照组(P<0.05)。治疗2个月后，试验组VSS评分低于对照组(P<0.05)。结论：与湿润烧伤膏联合自体微粒皮种植术治疗深Ⅱ度烧伤效果相比，水凝胶敷料联合自体微粒皮种植术治疗深Ⅱ度烧伤可提升创面愈合速度，降低血清致痛因子水平，减少瘢痕形成，且不良反应较少，值得临床应用。

    [关键词]深Ⅱ度烧伤；湿润烧伤膏；水凝胶敷料；自体微粒皮种植术；创面愈合

    [中图分类号]R644? ? [文献标志码]A? ? [文章编号]1008-6455(2023)08-0052-03

    To Compare the Effects of Two Different Dressings Combined with Autologous Microskin Grafting in the Treatment of Deep Degree-Ⅱ Burn

    WANG Lin，CHEN Jianli，GAO Xiaochun，ZOU Caixue

    (Department of Plastic and Burn Surgery，Dazhou Central Hospital，Dazhou 635000，Sichuan，China)

    Abstract： Objective? To explore the curative effect of two different dressings combined with autologous micro-skin grafting on deep degree-II burn. Methods? 90 patients with deep degree-II burn treated in the author's hospital from September 2018 to October 2020 were selected and divided into control group and experimental group according to the random number table method ......