张艾丽 方杰 王元秋 颜廷凯 黄银浩 王娟

    [摘要]目的：评估纳晶微针联合5%米诺地尔酊治疗成人斑秃的疗效及安全性。方法：将入选的68例成人斑秃患者随机分为治疗组36例，对照组32例，对照组单纯外用5%米诺地尔酊治疗，治疗组采用外用5%米诺地尔酊联合纳晶微针促渗导入治疗，对比两组患者的临床疗效及安全性。结果：治疗组有效率为83.33%，对照组有效率71.88%，差异无统计学意义(P>0.05)，治疗组治愈率为63.89%，对照组治愈率59.38%，差异无统计学意义(P>0.05)。治疗组的起效时间短于对照组(P<0.05)。结论：纳晶微针联合5%米诺地尔酊治疗成人斑秃安全、有效，较单用5%米诺地尔酊起效快。

    [关键词]纳晶微针；5%米诺地尔酊；斑秃；疗效观察

    [中图分类号]R758.71? ? [文献标志码]A? ? [文章编号]1008-6455(2023)08-0085-03

    Clinical Observation of Nanocrystalline Microneedle Combined with 5% Minoxidil Tincture in the Treatment of Adult Alopecia Areata

    ZHANG Aili，FANG Jie，WANG Yuanqiu，YAN Tingkai，HUANG Yinhao，WANG Juan

    (Department of Dermatology，the First People's Hospital of Bijie，Bijie 551700，Guizhou，China)

    Abstract： Objective? To evaluate the efficacy and safety of nanocrystalline microneedle combined with 5% minoxidil tincture in the treatment of adult alopecia areata. Methods? 68 adult patients with Alopecia areata were randomly divided into treatment group (n=36) and control group (n=32). The control group was treated with 5% minoxidil tincture ......