马雅宁 赵鹏 孟素玉 徐文虎 胡荔男 王康

    [摘要]目的：探討银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面的疗效。方法：选取149例深Ⅱ度烧伤感染性创面患者，依照乱数表法分为观察组(n=75例)和对照组(n=74例)，对照组给予复方多粘菌素B软膏治疗，观察组在对照组基础上加用银离子敷料治疗。统计比较两组创面恢复相关指标、创面疼痛程度、血清炎性因子和疼痛介质水平、临床疗效及瘢痕情况。结果：治疗后，观察组感染控制时间、住院时间、创面愈合时间均短于对照组(P<0.05)，治疗21 d后的创面愈合率高于对照组(P<0.05)。观察组治疗后各时间点疼痛评分均低于对照组(P<0.05)；治疗21 d后，观察组血清C反应蛋白、白介素-6、神经肽Y、前列腺素E2水平均低于对照组(P<0.05)，创面愈合总有效率高于对照组(P<0.05)；创面愈合后6个月，观察组温哥华瘢痕量表各评分及总分均低于对照组(P<0.05)。结论：银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面能促进创面愈合，减轻创面疼痛程度，并能有效抑制血清炎性因子、疼痛介质水平，减轻创面瘢痕程度，提升创面美学效果。

    [关键词]银离子敷料；复方多粘菌素B软膏；深Ⅱ度烧伤感染性创面；炎性因子；瘢痕

    [中图分类号]R644? ? [文献标志码]A? ? [文章编号]1008-6455(2024)04-0025-04

    Effects of Silver Ion Dressing Combined with Compound Polymyxin B Ointment in the Treatment of Deep Second-Degree Burn Infectious Wounds

    MA Yaning， ZHAO Peng， MENG Suyu， XU Wenhu， HU Linan， WANG Kang

    (Department of Burn and Plastic Surgery， Xingtai City Fifth Hospital， Xingtai 054000， Hebei， China)

    Abstract： Objective? To explore the effects of silver ion dressing and compound polymyxin B ointment in the treatment of burn infectious wounds. Methods? A total of 149 patients with deep partial-thickness burn infection wounds were selected and divided into observation group (n=75) and control group (n=74) according to the random number table method. The control group was treated with compound polymyxin B ointment ......