刘丹 李茂玉 吴丹

    [摘要]目的：分析富血小板血漿(Platelet-rich plasma，PRP)联合曲安奈德局部注射及瘢痕组织瓣修复术治疗瘢痕疙瘩的美学效果。方法：选取2017年2月-2021年11月遂宁市中心医院医疗美容科收治的瘢痕疙瘩患者85例，遵随机数字表法分为曲安奈德组42例(瘢痕组织瓣修复术联合曲安奈德局部注射)和联用PRP组43例(曲安奈德组基础上联合PRP治疗)。比较两组临床疗效，瘢痕恢复情况，疼痛及瘙痒情况和复发率，记录两组不良反应发生情况。结果：治疗后，联用PRP组治疗总有效率为97.67%，显著高于曲安奈德组的85.71%(P<0.05)；治疗后，两组色泽、柔软度、血管及厚度评分均降低(P<0.05)，且联用PRP组显著低于曲安奈德组(P<0.05)；治疗后，两组疼痛及瘙痒评分均降低(P<0.05)，且联用PRP组显著低于曲安奈德组(P<0.05)；两组不良反应发生率差异无统计学意义(P>0.05)；随访1年后，联用PRP组总复发率为2.33%，显著低于曲安奈德组的14.29%(P<0.05)。结论：PRP联合曲安奈德局部注射联合瘢痕组织瓣修复术治疗瘢痕疙瘩疗效确切，能有效促进瘢痕创面恢复，缓解疼痛及瘙痒，降低复发率。

    [关键词]富血小板血浆；曲安奈德；瘢痕疙瘩；瘢痕组织瓣修复术

    [中图分类号]R619.6? ? [文献标志码]A? ? [文章编号]1008-6455(2024)04-0079-04

    Analysis of the Efficacy of Topical Injection of Triamcinolone and Scar Tissue Flap Repair in the Treatment of Keloids

    LIU Dan， LI Maoyu， WU Dan

    (Department of Medical Cosmetology， Suining Central Hospital， Suining 629000， Sichuan， China)

    Abstract： Objective? To analyze the cosmetic effect of platelet-rich plasma (PRP) combined with topical injection of triamcinolone and scar tissue flap repair in the treatment of keloids. Methods? 85 patients with keloid treated in department of medical cosmetology of Suining Central Hospital from February 2017 to November 2021 were selected and divided into 42 cases in triamcinolone group (scar tissue flap repair combined with topical injection of triamcinolone) and 43 cases in united PRP group (PRP on the basis of triamcinolone group) according to the random number table method. The clinical efficacy ......