郭世凯 周子芙 李婧 毕见海

    [摘要]鲜红斑痣(Port-wine stain，PWS)是一种常见的先天性血管畸形病变，临床表现为压之可褪色的不规则红色斑片，约有75%的患者发病于头面部，其颜色可由初始的粉红色进展为鲜红、紫红色，部分患者还可出现局部皮肤的增厚、结节等表现，给患者及家属的社会心理及生理带来较大影响。海姆泊芬光动力疗法是一种无创疗法，被广泛应用于皮肤性疾病及肿瘤性疾病的治疗。近年来，海姆泊芬光动力疗法在PWS的治疗中广泛应用，并取得了显著成效，本文就光动力疗法治疗PWS的研究进展进行综述，以期为PWS的治疗提供理论依据。

    [关键词]鲜红斑痣；海姆泊芬光动力疗法；血管畸形；脉冲染料激光

    [中图分类号]R732.2? ? [文献标志码]A? ? [文章编号]1008-6455(2024)05-0195-03

    Research Progress of Himporfen Photodynamic Therapy for Port-wine Stain

    GUO Shikai1， ZHOU Zifu2， LI Jing1， BI Jianhai1

    ( 1.Department of Burn Plastic Surgery， Provincial Hospital Affiliated to Shandong First Medical University， Jinan 250021， Shandong， China; 2.Department of Burn Plastic Surgery， Provincial Hospital Affiliated to Shandong University， Jinan 250021， Shandong， China )

    Abstract： Port-wine stain is a common congenital vascular malformation disease. Its clinical manifestation is irregular red patches that can fade when pressed. About 75% of the patients occur on the head and face. Its color can change from the initial pink to dark red and purple red. Some patients can also have local skin thickening ......