[摘要]目的：探究负压创面治疗技术(Negative pressure wound therapy，NPWT)联合削痂植皮术修复深度烧伤后创面的疗效。方法：选取2020年1月-2023年1月笔者医院收治的112例深度烧伤患者，按随机数字表法分为实验组(56例)和对照组(56例)。对照组采用削痂植皮术治疗，实验组采用NPWT联合削痂植皮术进行治疗。统计比较两组患者临床疗效、创面愈合情况、疼痛评分[视觉模拟评分法(Visual analogue scale，VAS)]、外观满意度评分、炎症因子水平[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]、并发症及瘢痕情况[温哥华瘢痕量表(Vancouver scar scale，VSS)]。结果：治疗后，实验组临床疗效优于对照组，创面愈合时间短于对照组，差异均有统计学意义(P<0.05)；植皮术后7 d，实验组创面愈合率、皮片成活率、外观满意度评分均高于对照组(P<0.05)，疼痛VAS评分、TNF-α和IL-6水平均低于对照组(P<0.05)；治疗期间，实验组总并发症发生率低于对照组(P<0.05)；植皮术后6个月，实验组VSS各评分及总分均低于对照组(P<0.05)。结论：NPWT联合削痂植皮术修复深度烧伤后创面疗效良好，可有效促进创面愈合，降低疼痛感，减少瘢痕形成，改善患者预后，值得临床应用。

    [关键词]负压创面治疗技术；削痂；植皮；深度烧伤；创面

    [中图分类号]R622 [文献标志码]A [文章编号]1008-6455(2024)10-0089-04

    Application of Negative Pressure Wound Therapy Combined with Scab Removal and Skin Grafting in the Repair of Deep Burn Wounds

    FU Yongfeng1， WANG Jiaxin1， SHAN Nan1， ZHANG Xinyuan2

    ( 1.Department of Burn Plastic and Aesthetic Surgery， 2.Department of Oncology， Qinhuangdao First Hospital， Qinhuangdao 066000， Hebei， China )

    Abstract： Objective To explore the repair effect of negative pressure wound therapy (NPWT) combined with scab removal and skin grafting in wound after deep burn. Methods A total of 112 patients with deep burns admitted to the author's hospital from January 2020 to January 2023 were selected and divided into experimental group (56 cases) and control group (56 cases) according to the random number table method. The control group was treated with tangential excision and skin grafting ......