[摘要]目的：探讨点阵CO2激光联合30%冰醋酸治疗甲真菌病的疗效及对皮肤美观度的影响。方法：选择2022年2月-2023年2月在笔者医院皮肤科就诊的58例甲真菌病患者。对照组病甲外用30%冰醋酸进行治疗，研究组为点阵CO2激光联合30%冰醋酸进行治疗，随访3个月。治疗3个月后评估两组疗效，比较两组治疗满意度，分别于治疗1个月、3个月进行病变/健康甲板长度测量。比较两组不良反应发生情况。结果：研究组治疗总有效率为68.97%，显著高于对照组的41.38%(P<0.05)；研究组治疗总满意度为65.52%，显著高于对照组的37.93%(P<0.05)；研究组治疗3个月、6个月病变甲板长度均明显短于对照组(P<0.05)，健康甲板长度均明显长于对照组(P<0.05)；治疗期两组均无甲下出血、缺损等不良反应发生；无肝功肾功能异常；尿、血常规在正常范围。结论：点阵CO2激光结合30%冰醋酸治疗在治疗甲真菌病时，能够有效保护患者的皮肤屏障功能和提升美观度。

    [关键词]点阵CO2激光；30%冰醋酸；甲真菌病；疗效；皮肤屏障功能；美观度

    [中图分类号]R756.4" " [文献标志码]A" " [文章编号]1008-6455(2024)12-0128-03

    Analysis of the Efficacy of Fractional CO2 Laser Combined with 30% Glacial Acetic Acid in the Treatment of Onychomycosis

    LI Da， TU Yaling， ZHAO Juhua

    ( Department of Dermatology， Nanchong Central Hospital， Nanchong 637000， Sichuan， China )

    Abstract： Objective" To investigate the efficacy and aesthetic impact of fractional CO2 laser combined with 30% glacial acetic acid in the treatment of onychomycosis. Methods" A total of 58 patients with onychomycosis who attended the dermatology clinic of the author’s hospital from February 2022 to February 2023 were selected. The control group received topical treatment with 30% glacial acetic acid ......